NCT05652751 is a NA clinical trial of nerve growth factor in Ischemic Stroke, sponsored by The Third Affiliated hospital of Zhejiang Chinese Medical University.

Who is sponsoring NCT05652751?

NCT05652751 is sponsored by The Third Affiliated hospital of Zhejiang Chinese Medical University.

What drugs are being tested in NCT05652751?

Interventions in NCT05652751: nerve growth factor, physiological saline, EA, sham EA.

What condition does NCT05652751 study?

NCT05652751 studies Ischemic Stroke.

Is NCT05652751 still recruiting?

NCT05652751 is currently status unknown. Last updated 15 December 2022.

Last reviewed 2022-12-15 · How we verify

NCT05652751

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke

Status unknown NA Last updated 15 December 2022

What this trial tests

NA trial testing nerve growth factor in Ischemic Stroke in 120 participants. Status unknown.

Timeline

1 March 2022

Primary endpoint
1 February 2023

1 June 2023

Quick facts

Lead sponsor	The Third Affiliated hospital of Zhejiang Chinese Medical University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	120
Start date	1 March 2022
Primary completion	1 February 2023
Estimated completion	1 June 2023
Sites	1 location across China

Drugs / interventions tested

nerve growth factor — full drug profile →
physiological saline — full drug profile →
EA
sham EA

Conditions studied

Ischemic Stroke — all drugs for Ischemic Stroke →

Sponsor

The Third Affiliated hospital of Zhejiang Chinese Medical University

Who can join

Adults 50 to 80, any sex, with Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but it has little effect on stroke because of the blood-brain barrier (BBB). Electroacupuncture (EA) has been used for stroke, while there is no significant clinical effect for recovery phrase. Consequently, we will conduct a multicentre, randomised, controlled, assessor-blinded clinical trial to assess the effectiveness and safety of EA combined with NGF treatment on ischemic stroke recovery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A review: Carrier-based hydrogels containing bioactive molecules and stem cells for ischemic stroke therapy.
Yin W, Jiang Y, Ma G, Mbituyimana B, et al · · 2025 · cited 5× · PMID 40124600 · DOI 10.1016/j.bioactmat.2025.01.014

Verify or expand the search:

Other recruiting trials for Ischemic Stroke

Currently open trials in the same condition.

NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting

Other The Third Affiliated hospital of Zhejiang Chinese Medical University trials

Trials by the same sponsor.

NCT07522567 — Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures · NA · not yet recruiting
NCT07496580 — Efficacy Evaluation of Electroacupuncture in the Treatment of Functional Dyspepsia · NA · not yet recruiting
NCT07325045 — Biomechanical Study of Lever Positioning Manipulation on Scoliosis · NA · not yet recruiting
NCT07250308 — Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms · recruiting
NCT07308951 — Effect of Patient-Controlled Transcutaneous Electrical Acupoint Stimulation on Quality of Life in Chronic Cancer Pain · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05652751 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The Third Affiliated hospital of Zhejiang Chinese Medical University
Last refreshed: 15 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05652751.

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