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A Study to Understand the Effect of a Study Medicine Called ARV-471 on Rosuvastatin in Healthy Adults
The purpose of this study is to understand if ARV-471 affects how a BCRP substrate (rosuvastatin) gets into the body in healthy adults. All participants in this study will receive one dose of rosuvastatin alone by mouth in Period 1. In Period 2, everyone will receive one dose of ARV-471 by mouth 90 min before one dose of rosuvastatin by mouth. The levels of rosuvastatin in Period 1 will be compared to the levels of rosuvastatin in Period 2 to determine if ARV-471 affects how rosuvastatin gets into the body differently in healthy adults. All participants will stay at the study clinic for 10 days and 9 nights.
Details
| Lead sponsor | Pfizer |
|---|---|
| Phase | PHASE1 |
| Status | COMPLETED |
| Enrolment | 12 |
| Start date | Fri Dec 09 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Mar 06 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Healthy
Interventions
- ARV-471
- Rosuvastatin
Countries
United States