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NCT05651204
GABA Biomarkers in Dravet Syndrome
trial testing GABA Blood Level in Dravet Syndrome in 36 participants. Currently enrolling.
8 September 2024
Quick facts
| Lead sponsor | Cook Children's Health Care System |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 36 |
| Start date | 8 September 2022 |
| Primary completion | 8 September 2024 |
| Estimated completion | 8 September 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- GABA Blood Level
Conditions studied
- Dravet Syndrome — all drugs for Dravet Syndrome →
Sponsor
Cook Children's Health Care System
Who can join
Under 18, any sex, with Dravet Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will non-invasively obtain levels of GABA in the brain of children with SCN1A+DS and neurodeveloping children through evoked and induced cortical responses, correlate them with the BOLD responses, and with the levels of GABA in their blood.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05651204
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dravet Syndrome
Currently open trials in the same condition.
- NCT07251673 — Longitudinal Study of Phenotypic and Developmental Severity in Patients With Dravet Syndrome With SCN1A Gene Mutation · recruiting
- NCT06401538 — BMB-101 in Absence Epilepsy and DEE · Phase 2 · recruiting
- NCT06660394 — A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS) · Phase 3 · recruiting
- NCT06118255 — A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less · Phase 3 · active not recruiting
- NCT06504511 — SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom · recruiting
Other Cook Children's Health Care System trials
Trials by the same sponsor.
- NCT07567053 — Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study · NA · not yet recruiting
- NCT07394036 — Effect of Ipratropium Bromide on EILO · Phase 2 · not yet recruiting
- NCT07121920 — Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD · NA · not yet recruiting
- NCT06450158 — Robot-assisted Training in Children With CP · NA · recruiting
- NCT06424158 — Massage Therapy After Thoracic or Lumbar Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05651204 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cook Children's Health Care System
- Last refreshed: 14 December 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05651204.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing