NCT05651009 (ClessTKA) is a NA clinical trial of TKA in Knee Osteoarthritis, sponsored by Helse Møre og Romsdal HF.

Who is sponsoring NCT05651009?

NCT05651009 is sponsored by Helse Møre og Romsdal HF.

What drugs are being tested in NCT05651009?

Interventions in NCT05651009: TKA.

What condition does NCT05651009 study?

NCT05651009 studies Knee Osteoarthritis.

Is NCT05651009 still recruiting?

NCT05651009 is currently active, enrolled. Last updated 27 August 2024.

Last reviewed 2024-08-27 · How we verify

NCT05651009: ClessTKA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of the in Vivo Stability of 2 Cementless TKA Designs

Active, enrolled NA Last updated 27 August 2024

What this trial tests

NA trial testing TKA in Knee Osteoarthritis in 50 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

6 December 2022

Primary endpoint
25 June 2028

1 January 2033

Quick facts

Lead sponsor	Helse Møre og Romsdal HF
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	50
Start date	6 December 2022
Primary completion	25 June 2028
Estimated completion	1 January 2033
Sites	1 location across Norway

Drugs / interventions tested

Conditions studied

Knee Osteoarthritis — all drugs for Knee Osteoarthritis →

Sponsor

Helse Møre og Romsdal HF — full company profile →

Who can join

Adults 50 to 75, any sex, with Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this randomized controlled trial is to analyze the stability of a cementless Total Knee Arthroplasty (TKA) over time and compare it to a well-documented implant in patients with knee osteoarthritis. The main aim is to answer if there is a difference in stability over time as a measure of long time survivorship in these 2 implants. 50 participants will be randomly allocated to receive either the Triathlon Tritanium (Stryker) or the Global Medacta Knee Sphere (GMK Sphere, Medacta) 3D printed cementless TKAs.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Computed tomography-based radiostereometric analysis achieves sufficient precision for femoral implants in total knee arthroplasty: a randomized controlled trial.
Øhrn FD, Engseth LHW, Pripp AH, Frøseth Aae T, et al · · 2025 · cited 1× · PMID 41316419 · DOI 10.1186/s13018-025-06517-1
Dose reduction does not impact precision of CT-RSA in tibial components in total knee arthroplasty: a randomized controlled trial.
Bru F, Engseth LHW, Pripp AH, Schulz A, et al · · 2026 · PMID 41840645 · DOI 10.1186/s13018-026-06801-8

Verify or expand the search:

Other trials of TKA

Trials testing the same drug.

NCT03549962 — Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Co · completed
NCT03848520 — Survey of Running Following a TKA · completed
NCT03364790 — Correlation Between the Lower Extremities and Lumbar Degenerative Diseases of the Elderly · NA · unknown
NCT03044457 — Forgotten Joint Score After Reversed Gap Technique · NA · unknown
NCT02405104 — Chlorzoxazone in Hip and Knee Arthroplasty · Phase 4 · completed

Other recruiting trials for Knee Osteoarthritis

Currently open trials in the same condition.

NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting

Other Helse Møre og Romsdal HF trials

Trials by the same sponsor.

NCT07381790 — Modern Technologies in Lower Respiratory Tract Infections in Children · recruiting
NCT07021274 — DBT Skill Training for Autistic Adults With Difficulties in Emotion Regulation. · NA · not yet recruiting
NCT06458374 — ATTR Cardiac Amyloidosis in a Selected Population · recruiting
NCT06507046 — The personalKNEE Trial · NA · recruiting
NCT06499038 — The Ace Avanteon Study - A Randomized Controled Trial · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05651009 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Helse Møre og Romsdal HF
Last refreshed: 27 August 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05651009.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing