Who is sponsoring NCT05648955?

NCT05648955 is sponsored by Nutricia Research.

What drugs are being tested in NCT05648955?

Interventions in NCT05648955: an enriched high protein and high energy oral nutrition supplement (ONS).

What condition does NCT05648955 study?

NCT05648955 studies Colorectal Cancer (CRC), Non-small Cell Lung Cancer (NSCLC).

Is NCT05648955 still recruiting?

NCT05648955 is currently status unknown. Last updated 28 July 2023.

Last reviewed 2023-07-28 · How we verify

NCT05648955: ALLIES

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of an Oral Nutritional Supplement on Muscle Mass During Anticancer Treatment

Status unknown EARLY_PHASE1 Last updated 28 July 2023

What this trial tests

EARLY_PHASE1 trial testing an enriched high protein and high energy oral nutrition supplement (ONS) in Colorectal Cancer (CRC) in 118 participants. Status unknown.

Timeline

31 March 2023

Primary endpoint
30 June 2025

30 June 2025

Quick facts

Lead sponsor	Nutricia Research
Phase	EARLY_PHASE1
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	supportive care
Enrollment	118
Start date	31 March 2023
Primary completion	30 June 2025
Estimated completion	30 June 2025
Sites	1 location across Ireland

Drugs / interventions tested

an enriched high protein and high energy oral nutrition supplement (ONS)

Conditions studied

Colorectal Cancer (CRC) — all drugs for Colorectal Cancer (CRC) →
Non-small Cell Lung Cancer (NSCLC) — all drugs for Non-small Cell Lung Cancer (NSCLC) →

Sponsor

Nutricia Research — full company profile →

Who can join

18 and older, any sex, with Colorectal Cancer (CRC) or Non-small Cell Lung Cancer (NSCLC). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Malnutrition and low muscle mass (sarcopenia) are common problems in patients with cancer. However, a low muscle mass is associated with negative clinical outcomes in patients with cancer. Therefore, it is very important to maintain muscle mass in this population. This study aims to investigate the effect of an oral nutritional supplement on skeletal muscle mass during anti-cancer treatment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.
Gao Z, Liu Y, Cui Y, Han Y, et al · · 2026 · cited 2× · PMID 40850675 · DOI 10.1016/j.jare.2025.08.034

Verify or expand the search:

Other recruiting trials for Colorectal Cancer (CRC)

Currently open trials in the same condition.

NCT07448142 — Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer · Phase 2 · recruiting
NCT07223047 — A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agent · Phase 1, PHASE2 · recruiting
NCT07106892 — Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects Wit · Phase 2 · recruiting
NCT07152210 — Clinical Study on the Safety and Preliminary Efficacy of CDH17/GUCY2C CAR-T in the Treatment of Patients With Advanced C · NA · recruiting
NCT07046468 — Smart Pill for Measuring Gut Health in Colon Inflammation and Colon Cancer · recruiting

Other Nutricia Research trials

Trials by the same sponsor.

NCT07243743 — Assessment of the Glycemic Responses to Nutritional Products-INQ-2526 · NA · completed
NCT06797349 — Glin4: Assessment of the Glycemic Responses to Nutritional Products · Phase 4 · completed
NCT06920550 — A Growth Artificial Intelligence Algorithm for leNgth and Weight Study · recruiting
NCT06628024 — Determination of the Postprandial Amino Acid Uptake Kinetics of Yoghurt Vs Milk. · NA · completed
NCT05731206 — Hypoallergenicity of a Hydrolyzed Protein Infant Formula · NA · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05648955 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nutricia Research
Last refreshed: 28 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05648955.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing