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NCT05648825
Transapical Beating-Heart Septal Myectomy for Symptomatic Nonobstructive Hypertrophic Cardiomyopathy
NA trial testing Transapical beating-heart septal myectomy in Nonobstructive Hypertrophic Cardiomyopathy in 100 participants. Participants enrolled and being followed up; not accepting new ones.
30 July 2025
Quick facts
| Lead sponsor | Xiang Wei |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 15 November 2022 |
| Primary completion | 30 July 2025 |
| Estimated completion | 30 December 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Transapical beating-heart septal myectomy
Conditions studied
- Nonobstructive Hypertrophic Cardiomyopathy — all drugs for Nonobstructive Hypertrophic Cardiomyopathy →
Sponsor
Xiang Wei
Who can join
12 and older, any sex, with Nonobstructive Hypertrophic Cardiomyopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary purpose of this study is to evaluate the feasibility, the safety and the efficacy of the transapical beating-heart myectomy for the treatment of apical hypertrophic cardiomyopathy. This is a prospective, single-arm, single-center study.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05648825
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transapical beating-heart septal myectomy
Trials testing the same drug.
- NCT05332691 — Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy · NA · recruiting
Other recruiting trials for Nonobstructive Hypertrophic Cardiomyopathy
Currently open trials in the same condition.
- NCT06580717 — ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy · Phase 4 · recruiting
Other Xiang Wei trials
Trials by the same sponsor.
- NCT06078410 — Neurologic Evaluation of Patients After Transapical Beating-Heart Septal Myectomy · unknown
- NCT05332691 — Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05648825 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xiang Wei
- Last refreshed: 8 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05648825.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing