Who is sponsoring NCT05648708?

NCT05648708 is sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital.

What condition does NCT05648708 study?

NCT05648708 studies Orthopedic Disorder, Total Knee Replacement, Post Operative Pain, Surgery.

What drugs are being tested in NCT05648708?

Interventions: Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride, Bupivacaine and prilocaine hydrochloride.

What is the status of NCT05648708?

NCT05648708 is currently COMPLETED.

Last reviewed 2025-06-08 · How we verify

Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery

NCT05648708 NA COMPLETED

Knee joints, one of the largest and most functional joints of the human body, have great features to provide ideal body posture and movement. In patients with knee osteoarthritis in whom pain and functional loss continue to increase despite conservative and medical burden, they are evaluated by orthopedic surgeons for surgical treatment. Total knee replacement (TKR) surgery is aimed to eliminate the existing pain, restore and carry the movements, to protect the characteristics of the deformities and the quality of life. Pain can be very severe after TKR surgery, which is very common in the middle and elderly patient population today. In the postoperative period, untreated pain prevents early physical therapy practices and restricts postoperative knee rehabilitation and recovery, but it also has negative effects on the respiratory, gastrointestinal, renal, and central nervous systems. Effective management of postoperative acute pain can reduce these complications and the risk of developing chronic pain. In this study, investigators hypothesized that combined adductor canal and sciatic nerve block, applied with postoperative ultrasound guidance to patients who will undergo TKR surgery under general anesthesia, will provide effective analgesia, less opioid consumption, and faster ambulation time, similar to combined femoral and sciatic nerve block.

Details

Lead sponsor	Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Phase	NA
Status	COMPLETED
Enrolment	68
Start date	Mon Nov 14 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Oct 23 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Orthopedic Disorder
Total Knee Replacement
Post Operative Pain
Surgery

Interventions

Combine Adductor Canal & Sciatic Nerve Block
Combine Femoral & Sciatic Nerve Block
Bupivacaine and prilocaine hydrochloride
Bupivacaine and prilocaine hydrochloride

Countries

Turkey (Türkiye)