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NCT05646472: SUNFRAIL+
ICT-supported Multidimensional Approach for Frailty Screening in Community-dwelling Individuals Aged ≥ 65 Years
trial testing Frailty multidimensional assessment in Frail Elderly Syndrome in 700 participants. Status unknown.
28 February 2024
Quick facts
| Lead sponsor | Federico II University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 700 |
| Start date | 1 January 2023 |
| Primary completion | 28 February 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 8 locations across Italy |
Drugs / interventions tested
- Frailty multidimensional assessment
Conditions studied
- Frail Elderly Syndrome — all drugs for Frail Elderly Syndrome →
Sponsor
Federico II University
Who can join
65 and older, any sex, with Frail Elderly Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
SUNFRAIL+ is a prospective observational cohort study aimed to carry out a multidimensional assessment of community-dwelling older adults, through an IT platform, which allows to connect the items of the SUNFRAIL frailty assessment tool with a cascading multidimensional in-depth assessment of the bio-psycho-social domains of frailty. It is a multicentric study. Seven centres will administer SUNFRAIL questionnaire to 100 older adults each and, according to the specific "alerts" triggered by the answers provided, older adults will be subjected to one or more validated in-depth tests in order to perform further diagnostic or dimensional evaluations.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Digital Health Service for Identification of Frailty Risk Factors in Community-Dwelling Older Adults: The SUNFRAIL+ Study Protocol.
De Luca V, Femminella GD, Leonardini L, Patumi L, et al · · 2023 · cited 6× · PMID 36900872 · DOI 10.3390/ijerph20053861 -
Preliminary results of a multidimensional approach to screen for frailty in community-dwelling older adults of eight Italian regions: the SUNFRAIL+ study.
De Luca V, Donnoli C, Formosa V, Carnevale E, et al · · 2025 · cited 2× · PMID 40302770 · DOI 10.3389/fpubh.2025.1543724 -
Digital interventions addressing the unmet needs of older adults with multimorbidity: a mixed-methods persona design approach.
De Luca V, Virgolesi M, Cuomo A, Lemmo D, et al · · 2025 · PMID 41334414 · DOI 10.3389/fpubh.2025.1637748
Verify or expand the search:
- PubMed search for NCT05646472
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Frail Elderly Syndrome
Currently open trials in the same condition.
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- NCT06444321 — INTEgRated Health CARE for Patients With Frailty and Heart Failure · NA · recruiting
- NCT05993754 — Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams · NA · recruiting
- NCT06496022 — Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome · active not recruiting
Other Federico II University trials
Trials by the same sponsor.
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- NCT07374861 — Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy · recruiting
- NCT07314684 — GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05646472 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federico II University
- Last refreshed: 13 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05646472.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing