Last reviewed · How we verify
NCT05644158: MIVA
Mitochondrial Function in Peripheral Arterial Disease
NA trial testing Revascularization in Peripheral Arterial Disease in 80 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | Medical University Innsbruck |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 80 |
| Start date | 1 November 2022 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 January 2025 |
| Sites | 1 location across Austria |
Drugs / interventions tested
- Revascularization
- Exercise therapy
Conditions studied
- Peripheral Arterial Disease — all drugs for Peripheral Arterial Disease →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
Medical University Innsbruck
Who can join
Adults 18 to 99, any sex, with Peripheral Arterial Disease or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to investigate the effect of different treatment strategies on mitochondrial function and to correlate in-vitro results to findings from in-vivo measurements of mitochondrial function. The authors hypothesize that interventional revascularization and therefore the restoration of blood and oxygen supply is more relevant to mitochondrial function compared to the effect of exercise training.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Role of PTEN-Induced Protein Kinase 1 as a Mitochondrial Dysfunction Regulator in Cardiovascular Disease Pathogenesis.
Gwon JG, Lee SM. · · 2024 · cited 9× · PMID 38486493 · DOI 10.5758/vsi.230116 -
A Randomized Control Trial Investigating the Effect of Different Treatment Strategies on Mitochondrial Function in Peripheral Arterial Disease: A Study Protocol.
Schoenherr L, Heidler J, Kluckner M, Lobenwein D, et al · · 2025 · PMID 39987612 · DOI 10.1016/j.jss.2025.01.014
Verify or expand the search:
- PubMed search for NCT05644158
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT04252950 — Community-based Exercise Following Revascularization for PAD · NA · recruiting
- NCT04939038 — Timing of Revascularization in Patients With Diabetic Foot Ulcer and Non-critical Peripheral Artery Disease · NA · terminated
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Currently open trials in the same condition.
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Other Medical University Innsbruck trials
Trials by the same sponsor.
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- NCT07434648 — Comparison of Mastectomy Expander Trial · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05644158 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University Innsbruck
- Last refreshed: 13 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05644158.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing