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NCT05644158: MIVA

Mitochondrial Function in Peripheral Arterial Disease

Status unknown NA Last updated 13 March 2024
What this trial tests

NA trial testing Revascularization in Peripheral Arterial Disease in 80 participants. Status unknown.

Timeline
1 November 2022
Primary endpoint
31 December 2024
31 January 2025

Quick facts

Lead sponsorMedical University Innsbruck
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposebasic science
Enrollment80
Start date1 November 2022
Primary completion31 December 2024
Estimated completion31 January 2025
Sites1 location across Austria

Drugs / interventions tested

Conditions studied

Sponsor

Medical University Innsbruck

Who can join

Adults 18 to 99, any sex, with Peripheral Arterial Disease or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to investigate the effect of different treatment strategies on mitochondrial function and to correlate in-vitro results to findings from in-vivo measurements of mitochondrial function. The authors hypothesize that interventional revascularization and therefore the restoration of blood and oxygen supply is more relevant to mitochondrial function compared to the effect of exercise training.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Role of PTEN-Induced Protein Kinase 1 as a Mitochondrial Dysfunction Regulator in Cardiovascular Disease Pathogenesis.
    Gwon JG, Lee SM. · · 2024 · cited 9× · PMID 38486493 · DOI 10.5758/vsi.230116
  2. A Randomized Control Trial Investigating the Effect of Different Treatment Strategies on Mitochondrial Function in Peripheral Arterial Disease: A Study Protocol.
    Schoenherr L, Heidler J, Kluckner M, Lobenwein D, et al · · 2025 · PMID 39987612 · DOI 10.1016/j.jss.2025.01.014

Verify or expand the search:

Other trials of Revascularization

Trials testing the same drug.

Other recruiting trials for Peripheral Arterial Disease

Currently open trials in the same condition.

Other Medical University Innsbruck trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05644158.

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