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NCT05638217
Efficacy of the Use of Silver Diamine Fluoride and Sodium Fluoride Varnish for the Treatment of Caries in Children
trial testing Silver diamine fluoride 38% followed by Sodium fluoride varnish 5% in Dental Caries in Children in 199 participants. Completed in 15 November 2023.
15 November 2023
Quick facts
| Lead sponsor | Universidad Mayor de San Simón |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 199 |
| Start date | 7 November 2022 |
| Primary completion | 15 November 2023 |
| Estimated completion | 15 November 2023 |
| Sites | 1 location across Bolivia |
Drugs / interventions tested
- Silver diamine fluoride 38% followed by Sodium fluoride varnish 5%
Conditions studied
- Dental Caries in Children — all drugs for Dental Caries in Children →
Sponsor
Universidad Mayor de San Simón
Who can join
Adults 4 to 12, any sex, with Dental Caries in Children. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to identify the efficacy of silver diamine fluoride 38% followed by sodium fluoride varnish 5% in a population with untreated dental caries age range 4 to 12 years old. The main questions to answer are * Efficacy of treatment of active tooth decay with the treatment protocol of 38% silver diamine fluoride and 5% sodium fluoride varnish. * Clinical evaluation of tooth decay treated with 38% silver diamine fluoride and 5% sodium fluoride varnish in quality of hardness, color change and caries progression. * Explore the association of treatment with 38% silver diamine fluoride and 5% sodium fluoride varnish with: i. Reduction of oral pain caused by the presence of carious lesions. ii. Improvement in gingival oral health. iii. Changes in general nutritional status through measurements of height, weight, hemoglobin levels and nutritional survey. The participants will be identified, charted (with nutritional surveys and parameters), as well as treated and compared in a six- and twelve-month period, where researchers will clinically identify the association between the use of this protocol and the efficacy of such, as well as other related nutritional aspects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05638217
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Dental Caries in Children
Currently open trials in the same condition.
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- NCT06558955 — Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries · NA · recruiting
- NCT06286501 — Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases · NA · recruiting
- NCT07009015 — Impact of Oral Health Program on Al-Lith Children's KAP · NA · recruiting
- NCT06545279 — The Success Rate and Acceptability of Conventional and Modified Hall Crowns Among Children and Parents · NA · active not recruiting
Other Universidad Mayor de San Simón trials
Trials by the same sponsor.
- NCT04836299 — Clinical Trial to "Study the Efficacy and Therapeutic Safety of Ivermectin: (SAINTBO) · Phase 2 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05638217 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Mayor de San Simón
- Last refreshed: 18 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05638217.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing