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NCT05635032: FIBRALUNG

Fibrosing ILD Biomarkers That Rule Acceleration

Status unknown Last updated 27 October 2023
What this trial tests

trial testing Comprehensive clinical assessment and biological samples collection in Pulmonary Fibrosis in 150 participants. Status unknown.

Timeline
1 March 2021
Primary endpoint
29 February 2024
31 March 2026

Quick facts

Lead sponsorUniversidade do Porto
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment150
Start date1 March 2021
Primary completion29 February 2024
Estimated completion31 March 2026
Sites1 location across Portugal

Drugs / interventions tested

Conditions studied

Sponsor

Universidade do Porto — full company profile →

Who can join

Adults 18 to 80, any sex, with Pulmonary Fibrosis or Sarcoidosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

FIBRALUNG is a prospective cohort study with biobank of samples from patients with pulmonary fibrosis, aiming to explore the molecular determinants of different clinical outcomes, acute exacerbations and mortality. We expect to gain deeper insight into fibroproliferative common pathways, particularly between idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis, paving the way for new biomarkers that reflect the progressive phenotype, that eventually will support new targeted therapies. Other idiopathic interstitial pneumonias, connective tissue disease-related interstitial lung diseases and sarcoidosis patients will be also recruited and their biological samples stored for further analyses.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases.
    Jaiswal A, Kooistra T, Pokatayev V, Bastos HN, et al · · 2026 · PMID 41576947 · DOI 10.1016/j.xgen.2025.101066

Verify or expand the search:

Other recruiting trials for Pulmonary Fibrosis

Currently open trials in the same condition.

Other Universidade do Porto trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05635032.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing