Last reviewed · How we verify
NCT05629078
Vision and Balance Changes After Bilateral Implantation of Toric IOLs
NA trial testing Toric intraocular lens Zeiss AT TORBI in Cataract Bilateral in 140 participants. Status unknown.
30 December 2024
Quick facts
| Lead sponsor | University of Plymouth |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 12 January 2024 |
| Primary completion | 30 December 2024 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Toric intraocular lens Zeiss AT TORBI
Conditions studied
- Cataract Bilateral — all drugs for Cataract Bilateral →
- Astigmatism Bilateral — all drugs for Astigmatism Bilateral →
Sponsor
University of Plymouth
Who can join
Adults 50 to 75, any sex, with Cataract Bilateral or Astigmatism Bilateral. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cataracts are the major cause of blindness in the world. Cataract surgery, being the most performed surgery in the world today, provide correction by extracting the natural lens from its capsular bag and replaced by an artificial intraocular lens (IOL) implantation. In the UK, almost all patients undergoing cataract surgery by the NHS are given monofocal intraocular lenses (IOLs) which do not correct corneal astigmatic error. It is estimated that around 20% of the population has over 1.50DC of corneal astigmatism. Uncorrected astigmatism not only increase spectacle dependency and reduce quality of life post surgically, but it also adversely affects the overall economic costs. Specialised toric IOLs offer the opportunity to correct pre-existing corneal astigmatism. Previous work has shown a link between reduced vision and balance or mobility. Full correction of refractive error may have greater impact on lifestyle than previously thought.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Human retinal secretome: A cross-link between mesenchymal and retinal cells.
Donato L, Scimone C, Alibrandi S, Scalinci SZ, et al · · 2023 · cited 6× · PMID 37545752 · DOI 10.4252/wjsc.v15.i7.665
Verify or expand the search:
- PubMed search for NCT05629078
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cataract Bilateral
Currently open trials in the same condition.
- NCT07468877 — This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to S · NA · recruiting
Other University of Plymouth trials
Trials by the same sponsor.
- NCT07446348 — The Effect of Nitrogen Narcosis on Motor Performance in Divers Who Have Sustained an Inner Ear Decompression Illness · not yet recruiting
- NCT07484958 — Co-designing a Stroke Rehabilitation Trial Toolkit · enrolling by invitation
- NCT07356271 — Effects of Mouthwashes on the Oral Microbiome and Systemic Health · EARLY_PHASE1 · not yet recruiting
- NCT06894966 — Towards a Targeted Ultrasound Neuromodulation Intervention for Alcohol Abuse Disorders · NA · not yet recruiting
- NCT07274189 — Periodontal Health and Sodium Bicarbonate Toothpaste · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05629078 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Plymouth
- Last refreshed: 28 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05629078.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing