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NCT05628766
Thiol/Disulphide Homeostasis in Unexplained Infertility
trial testing complete blood count in Oxidative Stress in 82 participants. Completed in 21 April 2023.
21 April 2023
Quick facts
| Lead sponsor | Siirt University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 82 |
| Start date | 30 November 2022 |
| Primary completion | 21 April 2023 |
| Estimated completion | 21 April 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- complete blood count
Conditions studied
- Oxidative Stress — all drugs for Oxidative Stress →
- Infertility — all drugs for Infertility →
- Antioxidative Stress — all drugs for Antioxidative Stress →
Sponsor
Siirt University
Who can join
Adults 18 to 35, female only, with Oxidative Stress or Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim in this study is to determine whether there is a relationship between Thiol / Disulphide levels in primary infertile patients and comparing them with infertile patients and the control group. For this purpose, 41 women followed up with the diagnosis of primary infertility in Siirt Training and Research Hospital between November 2022 and January 2023 will be included in the study. The same number of (n:41) non-infertile control women will be included. Age, pregnancy history and medical history of both groups will be recorded. FSH, LH, E2, TSH, and prolactin levels taken routinely in these patients will be examined. Thiol/disulphide levels in the blood will be checked by taking whole blood from these patients. In the light of the information thus obtained, the investigator plan to determine whether there is a relationship between oxidant/antioxidant balance in primary infertile patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The role of thiol/disulfide homeostasis in unexplained primary infertile patients: A prospective cohort study.
Aksin Ş, Yilmaz M. · · 2025 · PMID 40020144 · DOI 10.1097/md.0000000000041641
Verify or expand the search:
- PubMed search for NCT05628766
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05628766 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Siirt University
- Last refreshed: 25 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05628766.
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