NCT05627128 (DAIN) is a NA clinical trial of DAIN in Crohn Disease, sponsored by University of Massachusetts, Worcester.

Who is sponsoring NCT05627128?

NCT05627128 is sponsored by University of Massachusetts, Worcester.

What drugs are being tested in NCT05627128?

Interventions in NCT05627128: DAIN.

What condition does NCT05627128 study?

NCT05627128 studies Crohn Disease.

Is NCT05627128 still recruiting?

NCT05627128 is currently active, enrolled. Last updated 17 April 2026.

Last reviewed 2026-04-17 · How we verify

NCT05627128: DAIN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Culturally Tailored Dietary Intervention to Treat Crohn's Disease

Active, enrolled NA Last updated 17 April 2026

What this trial tests

NA trial testing DAIN in Crohn Disease in 150 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

6 September 2022

Primary endpoint
31 May 2025

30 November 2026

Quick facts

Lead sponsor	University of Massachusetts, Worcester
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	150
Start date	6 September 2022
Primary completion	31 May 2025
Estimated completion	30 November 2026
Sites	2 locations across Puerto Rico, United States

Drugs / interventions tested

DAIN

Conditions studied

Crohn Disease — all drugs for Crohn Disease →

Sponsor

University of Massachusetts, Worcester

Who can join

Adults 21 to 65, any sex, with Crohn Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of the study is to test the efficacy of a dietary intervention in inducing clinical response and remission for patients with Crohn's disease in a randomized controlled trial. The intervention diet: DAIN has been adapted from the Inflammatory Bowel Disease Anti-Inflammatory Diet or IBD-AID™ taking into account the food availability and preferences of Puerto Ricans. DAIN also includes traditional foods commonly consumed in the typical Puerto Rican diet while maintaining the fundamental components of the IBD-AID™.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

DietaAnti-Inflamatoria or DAIN: A Crohn's disease management strategy tailored for Puerto Ricans.
Rojas Correa M, Estremera L, Yap Y, Díaz-Díaz LM, et al · · 2023 · cited 2× · PMID 37388217 · DOI 10.1016/j.conctc.2023.101162

Verify or expand the search:

Other recruiting trials for Crohn Disease

Currently open trials in the same condition.

NCT06953791 — Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Pat · Phase 2 · recruiting
NCT07310095 — A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD) · Phase 4 · recruiting
NCT07364734 — Epidemiological Characteristics and Efficacy Evaluation of Difficult-To-Treat Crohn's Disease · recruiting
NCT07170462 — Cranberry and Gut Health in Crohn's Disease · EARLY_PHASE1 · recruiting
NCT07196722 — A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease · Phase 2, PHASE3 · recruiting

Other University of Massachusetts, Worcester trials

Trials by the same sponsor.

NCT07431528 — Dementia and Storytelling in Vietnam · NA · not yet recruiting
NCT07060664 — Study on Outcomes of Proximal Humerus Fractures · NA · not yet recruiting
NCT07520110 — Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis · Phase 3 · not yet recruiting
NCT06100809 — Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts · NA · not yet recruiting
NCT06246539 — Impact of a Virtual Reality-based Mindfulness Program on Clinician Wellness · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05627128 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Massachusetts, Worcester
Last refreshed: 17 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05627128.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing