NCT05626998 is a Phase 4 clinical trial of Dexmedetomidine in Anesthesia, sponsored by Ain Shams University.

Who is sponsoring NCT05626998?

NCT05626998 is sponsored by Ain Shams University.

What drugs are being tested in NCT05626998?

Interventions in NCT05626998: Dexmedetomidine, Gabapentin.

What condition does NCT05626998 study?

NCT05626998 studies Anesthesia.

Is NCT05626998 still recruiting?

NCT05626998 is currently completed. Last updated 30 August 2023.

Last reviewed 2023-08-30 · How we verify

NCT05626998

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

Completed Phase 4 Last updated 30 August 2023

What this trial tests

Phase 4 trial testing Dexmedetomidine in Anesthesia in 153 participants. Completed in 30 April 2023.

Timeline

1 November 2022

Primary endpoint
30 April 2023

30 April 2023

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	153
Start date	1 November 2022
Primary completion	30 April 2023
Estimated completion	30 April 2023
Sites	1 location across Egypt

Drugs / interventions tested

Dexmedetomidine (dexmedetomidine) — full drug profile →
Gabapentin (Gabapentin) — full drug profile →

Conditions studied

Anesthesia — all drugs for Anesthesia →

Sponsor

Ain Shams University

Who can join

Adults 18 to 40, any sex, with Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To compare the effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

"The effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty". A prospective, randomized, double-blind controlled trial.
Abdelaziz TSA, Mohammed Elsayed HE, Kamal Eldin DM, Ibrahim IM. · · 2025 · cited 1× · PMID 39891093 · DOI 10.1186/s12871-025-02914-5

Verify or expand the search:

Other trials of Dexmedetomidine

Trials testing the same drug.

NCT06824077 — Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle · EARLY_PHASE1 · not yet recruiting
NCT07398066 — DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) · NA · not yet recruiting
NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
NCT07306702 — Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients · Phase 4 · withdrawn
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting

Other recruiting trials for Anesthesia

Currently open trials in the same condition.

NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07290205 — Remimazolam NeuroImaging · EARLY_PHASE1 · recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
NCT07443254 — Prospective IR-led Sedation Feasibility · Phase 1, PHASE2 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05626998 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 30 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05626998.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing