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NCT05624736

Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning

Status unknown Last updated 22 November 2022
What this trial tests

trial testing multi-parametric magnetic resonance imaging scan in Astrocytoma in 500 participants. Status unknown.

Timeline
20 November 2022
Primary endpoint
1 May 2023
1 May 2025

Quick facts

Lead sponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment500
Start date20 November 2022
Primary completion1 May 2023
Estimated completion1 May 2025
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Who can join

Adults 18 to 90, any sex, with Astrocytoma or Glioblastoma Multiforme. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a restrospective study to establish a deep learning model based on multi-parametric magnetic resonance imaging scans to predict Grade, histopathologic type and genotype of adult diffuse Glioma.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Identification of intrinsic imaging subtypes using clustering analysis based on dynamic contrast-enhanced magnetic resonance imaging radiomics features for gliomas: preliminary associations with gene expression profiles.
    Zhou J, Duan S, Zhu Z, Wang H, et al · · 2025 · cited 3× · PMID 40384650 · DOI 10.21037/qims-24-1459
  2. Fully automated Res3DNet model to predict IDH mutation of gliomas from whole-brain MRI free of tumor segmentation.
    Zhu Z, Liu Y, Song Y, Zhou J, et al · · 2026 · PMID 41531733 · DOI 10.1016/j.isci.2025.114373
  3. OMT and tensor SVD-based deep learning model for segmentation and predicting genetic markers of glioma: A multicenter study.
    Zhu Z, Wang H, Li T, Huang TM, et al · · 2025 · PMID 40627394 · DOI 10.1073/pnas.2500004122

Verify or expand the search:

Other recruiting trials for Astrocytoma

Currently open trials in the same condition.

Other The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School trials

Trials by the same sponsor.

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