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NCT05619055

The Intestinal Dysbacteriosis in the Pathogenesis of Necrotizing Enterocolitis

Status unknown Last updated 16 November 2022
What this trial tests

trial testing Routine treatment in Necrotizing Enterocolitis of Newborn in 30 participants. Status unknown.

Timeline
5 November 2022
Primary endpoint
31 March 2025
31 March 2025

Quick facts

Lead sponsorZuohui Zhao
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment30
Start date5 November 2022
Primary completion31 March 2025
Estimated completion31 March 2025
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Zuohui Zhao

Who can join

Adults 5 Days to 2 Months, any sex, with Necrotizing Enterocolitis of Newborn. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Study Description The goal of this observational study is to detect intestinal flora and the metabolic products in premature infants diagnosed as necrotizing enterocolitis. The main questions it aims to answer are: * 1\. Whether there is intestinal flora in the stool of premature infants. * 2\. Are there dysregulated intestinal flora and their metabolic products in premature infants diagnosed as necrotizing enterocolitis. * 3\. The detailed role and underlying mechanism of the intestinal dysbacteriosis and the metabolic products in premature infants diagnosed as necrotizing enterocolitis. Participants, premature infants diagnosed as necrotizing enterocolitis (NEC group), will be asked to collect stool (usually 2 times) for intestinal flora analysis. If there is a comparison group: Researchers will compare premature infants without necrotizing enterocolitis (control group) to see if their intestinal flora and the metabolic products also changed as their NEC counterparts.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Data sources for this page

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