Who is sponsoring NCT05617716?

NCT05617716 is sponsored by University of Oklahoma.

What drugs are being tested in NCT05617716?

Interventions in NCT05617716: Conventional external beam radiation therapy dose (EBRT), Spine radiosurgery/stereotactic body radiation therapy standard dose, Spine radiosurgery/stereotactic body radiation therapy high dose.

What condition does NCT05617716 study?

NCT05617716 studies Metastatic Neoplasm to the Spine, Metastatic Neoplasm.

Is NCT05617716 still recruiting?

NCT05617716 is currently recruiting now. Last updated 20 October 2025.

Last reviewed 2025-10-20 · How we verify

NCT05617716: SPORTSMEN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Spine Radiosurgery for Symptomatic Metastatic Neoplasms

Recruiting now Phase 2 Last updated 20 October 2025

What this trial tests

Phase 2 trial testing Conventional external beam radiation therapy dose (EBRT) in Metastatic Neoplasm to the Spine in 240 participants. Currently enrolling.

Timeline

9 September 2025

Primary endpoint
30 September 2028

30 September 2029

Quick facts

Lead sponsor	University of Oklahoma
Phase	Phase 2
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	240
Start date	9 September 2025
Primary completion	30 September 2028
Estimated completion	30 September 2029
Sites	2 locations across United States

Drugs / interventions tested

Conventional external beam radiation therapy dose (EBRT)
Spine radiosurgery/stereotactic body radiation therapy standard dose
Spine radiosurgery/stereotactic body radiation therapy high dose

Conditions studied

Metastatic Neoplasm to the Spine — all drugs for Metastatic Neoplasm to the Spine →
Metastatic Neoplasm — all drugs for Metastatic Neoplasm →

Sponsor

University of Oklahoma

Who can join

18 and older, any sex, with Metastatic Neoplasm to the Spine or Metastatic Neoplasm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to compare three types of radiation therapy for cancer that has spread to the spine. The two types of radiation therapy used in this trial are External Beam Radiation Therapy (EBRT) and Stereotactic Body Radiation Therapy (SBRT). EBRT delivers tightly targeted radiation beams from outside the body. SBRT is a specialized type of radiation therapy that allows high doses of radiation to small targets. This study will include standard dose SBRT and higher dose SBRT. Each participant will be randomly assigned to either EBRT, standard dose SBRT, or higher dose SBRT.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Spine Patient Optimal Radiosurgery Treatment for Symptomatic Metastatic Neoplasms (SPORTSMEN): a randomized phase II study protocol.
McClelland S, Sun Y, Spratt DE. · · 2023 · cited 10× · PMID 37795393 · DOI 10.5603/rpor.a2023.0037
An Inpatient Metastatic Spine Neoplasm Score for assessing the appropriate modality of radiation therapy intervention.
McClelland S. · · 2024 · cited 1× · PMID 39895961 · DOI 10.5603/rpor.101991
Establishing a Protocol to Increase Racial/Ethnic Under-Represented Minority Enrollment on an Active Radiation Oncology Multicenter Randomized Clinical Trial.
Gardner UG, Gardner UG, Brawley OW, Obi EE, et al · · 2025 · PMID 39930584 · DOI 10.1097/coc.0000000000001174
Impact of National Comprehensive Cancer Network Guidelines Inclusion of Level 1 Evidence on Insurance Denial for Randomized Controlled Trial Patients with Metastatic Spine Disease.
Gardner UG, Brately MM, Zuhour RJ, Sun Y, et al · · 2024 · PMID 39759561 · DOI 10.5603/rpor.102822

Verify or expand the search:

Other University of Oklahoma trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05617716 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Oklahoma
Last refreshed: 20 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05617716.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing