NCT05616507 (FIRILI) is a NA clinical trial of fucoidan in Radiation Toxicity, sponsored by Taipei Medical University WanFang Hospital.

Who is sponsoring NCT05616507?

NCT05616507 is sponsored by Taipei Medical University WanFang Hospital.

What drugs are being tested in NCT05616507?

Interventions in NCT05616507: fucoidan.

What condition does NCT05616507 study?

NCT05616507 studies Radiation Toxicity.

Is NCT05616507 still recruiting?

NCT05616507 is currently status unknown. Last updated 15 November 2022.

Last reviewed 2022-11-15 · How we verify

NCT05616507: FIRILI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oligo-Fucoidan Decrease Lung Radiation Damage

Status unknown NA Last updated 15 November 2022

What this trial tests

NA trial testing fucoidan in Radiation Toxicity in 100 participants. Status unknown.

Timeline

30 March 2022

Primary endpoint
30 December 2024

30 December 2025

Quick facts

Lead sponsor	Taipei Medical University WanFang Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	30 March 2022
Primary completion	30 December 2024
Estimated completion	30 December 2025
Sites	1 location across Taiwan

Drugs / interventions tested

fucoidan — full drug profile →

Conditions studied

Radiation Toxicity — all drugs for Radiation Toxicity →

Sponsor

Taipei Medical University WanFang Hospital

Who can join

Adults 20 to 90, any sex, with Radiation Toxicity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Fucoidan is FDA approved and in common use for treatment of angina. These studies will advance that work to human use. Successful mitigation of lung radiation damage and heart toxicity will improve the quality of life in veterans and non-veterans who are treated for lung cancer by radiation, and may also improve cure rates of radiation therapy for lung cancer.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects.
Turrini E, Maffei F, Fimognari C. · · 2023 · cited 18× · PMID 37233501 · DOI 10.3390/md21050307
Ionizing radiation: molecular mechanisms, biological effects, and therapeutic targets.
Wei W, Ren Y, Lan J, Yi J, et al · · 2026 · PMID 41507636 · DOI 10.1186/s43556-025-00358-4

Verify or expand the search:

Other trials of fucoidan

Trials testing the same drug.

NCT05623852 — The Impact of Oligo-Fucoidan in Cancer Cachexia and Sarcopenia · NA · unknown

Other recruiting trials for Radiation Toxicity

Currently open trials in the same condition.

NCT06950073 — Curatively Intended Thoracic Reirradiation · recruiting
NCT06311968 — The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor · Phase 2 · recruiting
NCT05530655 — A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy · EARLY_PHASE1 · recruiting
NCT06215495 — A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial · NA · recruiting
NCT06033183 — Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology · NA · recruiting

Other Taipei Medical University WanFang Hospital trials

Trials by the same sponsor.

NCT07401017 — The Effects of Rosuvastatin on Running Training Adaptation and Safety · NA · not yet recruiting
NCT07293442 — Pelvic Floor Muscle Exercise for Lower Urinary Tract Symptoms After Surgery for Benign Prostatic Hyperplasia. · NA · recruiting
NCT07150182 — Shared Decision-Making for Families in Critical Dialysis Initiation · NA · not yet recruiting
NCT06834425 — Efficacy of NSAID Peritendinous Injection for Acute Tendinitis · NA · active not recruiting
NCT06862297 — Prospective Study Between Polysomnography (PSG) and Novel Ultrasonic Jaw Tracking Device in Patients with Sleep Apnea · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05616507 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Taipei Medical University WanFang Hospital
Last refreshed: 15 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05616507.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing