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NCT05613075
Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
NA trial testing tooth extraction and socket preservation with demineralized tooth graft in Alveolar Bone Resorption in 30 participants. Completed in 29 November 2024.
30 October 2024
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 December 2022 |
| Primary completion | 30 October 2024 |
| Estimated completion | 29 November 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- tooth extraction and socket preservation with demineralized tooth graft
- tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
Conditions studied
- Alveolar Bone Resorption — all drugs for Alveolar Bone Resorption →
- Socket Preservation — all drugs for Socket Preservation →
- Bone Resorption — all drugs for Bone Resorption →
- Unrestorable Dentition — all drugs for Unrestorable Dentition →
Sponsor
Cairo University
Who can join
Adults 21 to 65, any sex, with Alveolar Bone Resorption or Socket Preservation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Many dentists, clinicians and researchers have conducted numerous trials, and put several materials and procedures under the test, in an attempt to preserve vertical and/or horizontal extraction sockets dimensions. The clinical consequences of post-extraction remodeling may affect the outcome of the ensuing therapies aimed at restoring the lost dentition, either by limiting the bone availability for ideal implant placement or by compromising the aesthetic result of the prosthetic restorations. In an attempt for ridge/socket preservation of a freshly extracted tooth socket/bed, this study aims to assess and compare between using autogenous tooth graft added with Hyaluronic acid, and the usage of the standardized autogenous tooth graft alone, regarding the potency, preservative feature, and quality of bone healing, density, and deposition. For a better restorative outcome using a delayed implant placement later on in the edentulous area.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Autogenous Demineralized Dentin Graft With High Molecular Weight Hyaluronic Acid in Ridge Preservation: Pilot Trial.
Hesham R, Shemais N, Saleh HA, Fawzy El-Sayed K. · · 2025 · cited 2× · PMID 41235610 · DOI 10.1111/cid.70100
Verify or expand the search:
- PubMed search for NCT05613075
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alveolar Bone Resorption
Currently open trials in the same condition.
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- NCT07028606 — Vertical Ridge Augmentation Using Computer-guided Sandwich Osteotomy Technique · Phase 1 · active not recruiting
- NCT05577663 — Guided Bone Regeneration in Alveolar Socket · NA · recruiting
Other Cairo University trials
Trials by the same sponsor.
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- NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05613075 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 5 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05613075.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing