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NCT05612100
Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients
trial testing Electronic Health Record Review in Breast Carcinoma in 170 participants. Currently enrolling.
30 June 2028
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 170 |
| Start date | 6 July 2022 |
| Primary completion | 30 June 2028 |
| Estimated completion | 30 June 2028 |
| Sites | 23 locations across United States |
Drugs / interventions tested
- Electronic Health Record Review
- Questionnaire Administration
- Survey Administration
Conditions studied
- Breast Carcinoma — all drugs for Breast Carcinoma →
Sponsor
Mayo Clinic
Who can join
18 and older, female only, with Breast Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates endocrine therapy-induced alopecia among postmenopausal and premenopausal female patients with breast cancer. Alopecia is one of the most feared side effects of cancer-directed therapy, causing distress in women starting treatment for breast cancer. While alopecia is a well-known side effect of many chemotherapy drugs, it has also been reported by women undergoing endocrine therapy. Despite the frequent reports of alopecia related to endocrine therapy, hair loss is rarely reported as a side effect of endocrine therapy and the exact characterization of alopecia is not well understood. By having postmenopausal and premenopausal breast cancer patients describe their hair loss symptoms experienced while undergoing endocrine therapy, researchers may be able to better characterize the incidence, timing, duration, and severity of alopecia and whether the different types of endocrine therapy cause more or less trouble in this regard.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Perceptions of Delayed Alopecia Among Breast Cancer Survivors.
Premji SK, Ruddy KJ, Vierkant RA, Larson N, et al · · 2025 · cited 2× · PMID 39592290 · DOI 10.1016/j.clbc.2024.09.008
Verify or expand the search:
- PubMed search for NCT05612100
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05612100 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 17 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05612100.
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