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NCT05610514
Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes
Phase 2 trial testing E-Cigarette in Chronic Obstructive Pulmonary Disease in 21 participants. Completed in 1 December 2023.
1 December 2023
Quick facts
| Lead sponsor | University of Vermont |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 21 |
| Start date | 28 April 2022 |
| Primary completion | 1 December 2023 |
| Estimated completion | 1 December 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- E-Cigarette — full drug profile →
- Financial Incentives
Conditions studied
- Chronic Obstructive Pulmonary Disease — all drugs for Chronic Obstructive Pulmonary Disease →
- Chronic Bronchitis — all drugs for Chronic Bronchitis →
- Emphysema — all drugs for Emphysema →
- Asthma-COPD Overlap Syndrome — all drugs for Asthma-COPD Overlap Syndrome →
Sponsor
University of Vermont
Who can join
40 and older, any sex, with Chronic Obstructive Pulmonary Disease or Chronic Bronchitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to compare the effects of e-cigarettes and continued smoking on pulmonary and cardiac outcomes in a population with established pulmonary disease.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Electronic cigarettes for smoking cessation.
Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2024 · cited 94× · PMID 38189560 · DOI 10.1002/14651858.cd010216.pub8 -
Electronic cigarettes for smoking cessation.
Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2025 · cited 32× · PMID 39878158 · DOI 10.1002/14651858.cd010216.pub9 -
Cardiopulmonary effects of combustible cigarettes and e-cigarettes in individuals with chronic obstructive pulmonary disease.
Katz BR, Menson KE, Medina N, O'Connor SD, et al · · 2026 · PMID 41343367 · DOI 10.1037/pha0000814
Verify or expand the search:
- PubMed search for NCT05610514
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Vermont trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05610514 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Vermont
- Last refreshed: 8 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05610514.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing