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NCT05610514

Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes

Completed Phase 2 Last updated 8 February 2024
What this trial tests

Phase 2 trial testing E-Cigarette in Chronic Obstructive Pulmonary Disease in 21 participants. Completed in 1 December 2023.

Timeline
28 April 2022
Primary endpoint
1 December 2023
1 December 2023

Quick facts

Lead sponsorUniversity of Vermont
PhasePhase 2
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designcrossover
Maskingnone
Primary purposebasic science
Enrollment21
Start date28 April 2022
Primary completion1 December 2023
Estimated completion1 December 2023
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Vermont

Who can join

40 and older, any sex, with Chronic Obstructive Pulmonary Disease or Chronic Bronchitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to compare the effects of e-cigarettes and continued smoking on pulmonary and cardiac outcomes in a population with established pulmonary disease.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Electronic cigarettes for smoking cessation.
    Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2024 · cited 94× · PMID 38189560 · DOI 10.1002/14651858.cd010216.pub8
  2. Electronic cigarettes for smoking cessation.
    Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2025 · cited 32× · PMID 39878158 · DOI 10.1002/14651858.cd010216.pub9
  3. Cardiopulmonary effects of combustible cigarettes and e-cigarettes in individuals with chronic obstructive pulmonary disease.
    Katz BR, Menson KE, Medina N, O'Connor SD, et al · · 2026 · PMID 41343367 · DOI 10.1037/pha0000814

Verify or expand the search:

Other recruiting trials for Chronic Obstructive Pulmonary Disease

Currently open trials in the same condition.

Other University of Vermont trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05610514.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing