Last reviewed · How we verify
NCT05609539: RESTHONE
Clinical Effectiveness of an Off-the-shelf Single REnal Scalloped sTent-graft for HOstile NEck Infrarenal Abdominal Aortic Aneurysm
trial testing Endovascular Aortic Repair (EVAR) in Abdominal Aortic Aneurysm in 50 participants. Completed in 28 September 2025.
28 September 2025
Quick facts
| Lead sponsor | Azienda Ospedaliero-Universitaria di Modena |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 February 2023 |
| Primary completion | 28 September 2025 |
| Estimated completion | 28 September 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Endovascular Aortic Repair (EVAR)
Conditions studied
- Abdominal Aortic Aneurysm — all drugs for Abdominal Aortic Aneurysm →
Sponsor
Azienda Ospedaliero-Universitaria di Modena — full company profile →
Who can join
18 and older, any sex, with Abdominal Aortic Aneurysm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this multicenter, observational cohort study is to evaluates the clinical effectiveness of a single-renal scallop custom-made stent-graft (TREO, Terumo Aortic, Sunrise, FL) to treat "hostile" AAA with mismatched renal arteries as actual standard of care in this Vascular Unit The main question it aims to answer are: if a dedicated devices could improve the results in the endovascular treatment of patients suffering to infrarenal abdominal aortic aneurism with a mismatched takeoff of the renal arteries. Participants responding to inclusion criteria will be treated as best clinical practice with a custom made device with a single scallop for the renal artery. The minimum follow-up requested, as standard clinical practice, was: 3-months, 12-18 months- and 5-years CTA; clinical and DUS examination at 6- and 12- and 36-months after the intervention and yearly thereafter. No comparison group was present.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05609539
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Endovascular Aortic Repair (EVAR)
Trials testing the same drug.
- NCT01480206 — Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR · completed
Other recruiting trials for Abdominal Aortic Aneurysm
Currently open trials in the same condition.
- NCT07476196 — Poland-Italy Aortic Research Bridge Real World Registry · recruiting
- NCT07473102 — PET Imaging of MMP Activation in AAA: Clinical Component · EARLY_PHASE1 · recruiting
- NCT06451315 — REGISTRY on the Implementation of Artificial Intelligence in the Automatic Analysis of Vascular Network Segmentation · recruiting
- NCT06001918 — Nectero EAST System Clinical Study · Phase 2, PHASE3 · recruiting
- NCT06008613 — 3D Holographic Guidance, Navigation, and Control for Endovascular Aortic Repair · NA · active not recruiting
Other Azienda Ospedaliero-Universitaria di Modena trials
Trials by the same sponsor.
- NCT06913530 — European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study · not yet recruiting
- NCT06883890 — Extended LH Administration · Phase 2 · not yet recruiting
- NCT07245537 — ENDOGYM: A Holistic Approach With Pelvic Floor Physiotherapy and Yoga for Endometriosis Pain Relief · completed
- NCT05922202 — Influence of Frailty on Cardiovascular Events and Mortality in Patients With COPD. · recruiting
- NCT06236568 — Impact of Graft Reconditioning With Hypothermic Machine Perfusion on HCC Recurrence After Liver Transplantation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05609539 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Azienda Ospedaliero-Universitaria di Modena
- Last refreshed: 2 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05609539.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing