NCT05605704 (Dia-Athr) is a Phase 2, PHASE3 clinical trial of Atherolive in Diabetes Mellitus, Type 2, sponsored by University of Monastir.

Who is sponsoring NCT05605704?

NCT05605704 is sponsored by University of Monastir.

What drugs are being tested in NCT05605704?

Interventions in NCT05605704: Atherolive, Placebo Atherolive.

What condition does NCT05605704 study?

NCT05605704 studies Diabetes Mellitus, Type 2.

Is NCT05605704 still recruiting?

NCT05605704 is currently recruiting now. Last updated 3 June 2025.

Last reviewed 2025-06-03 · How we verify

NCT05605704: Dia-Athr

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Olive Leaf Extracts in the Control of Diabet

Recruiting now Phase 2, PHASE3 Last updated 3 June 2025

What this trial tests

Phase 2, PHASE3 trial testing Atherolive in Diabetes Mellitus, Type 2 in 500 participants. Currently enrolling.

Timeline

1 January 2023

Primary endpoint
15 September 2025

15 December 2025

Quick facts

Lead sponsor	University of Monastir
Phase	Phase 2, PHASE3
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	500
Start date	1 January 2023
Primary completion	15 September 2025
Estimated completion	15 December 2025
Sites	1 location across Tunisia

Drugs / interventions tested

Atherolive — full drug profile →
Placebo Atherolive

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →

Sponsor

University of Monastir

Who can join

Adults 18 to 100, any sex, with Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will be carried out in 2 emergency departments (at the exit of the emergency room) and 2 external consultations (endocrinology of the CHU FB Monastir and diabetology consultation, Jemmal hospital). Patients over 18 years of age with: -Diabets

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Harnessing Nature's Toolbox: Naturally Derived Bioactive Compounds in Nanotechnology Enhanced Formulations.
Sanjai C, Gaonkar SL, Hakkimane SS. · · 2024 · cited 10× · PMID 39494011 · DOI 10.1021/acsomega.4c07756

Verify or expand the search:

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other University of Monastir trials

Trials by the same sponsor.

NCT07345156 — Congestion and LActate at diScHarge in Acute Heart Failure · not yet recruiting
NCT07181642 — Diaphragmatic Breathing for Sleep Bruxism in Adults: A Randomized Controlled Trial · NA · completed
NCT06980727 — Comparative Efficacy of IV Dexamethasone vs. Nebulized Salbutamol for Renal Colic Pain in the ED · Phase 3 · not yet recruiting
NCT06900972 — Effect of Colloids Versus Crystalloids on Heart Mechanics: a Double-blind Cross Over Randomized Trial · Phase 3 · enrolling by invitation
NCT06723002 — Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome · Phase 2, PHASE3 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05605704 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Monastir
Last refreshed: 3 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05605704.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing