NCT05600270 is a NA clinical trial of Angled guidewire in Bile Duct Diseases, sponsored by Neev Mehta.

Who is sponsoring NCT05600270?

NCT05600270 is sponsored by Neev Mehta.

What drugs are being tested in NCT05600270?

Interventions in NCT05600270: Angled guidewire, Straight guidewire.

What condition does NCT05600270 study?

NCT05600270 studies Bile Duct Diseases.

Is NCT05600270 still recruiting?

NCT05600270 is currently completed. Last updated 31 October 2024.

Are results published for NCT05600270?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2024-10-31 · How we verify

NCT05600270

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation

Completed NA Results posted Last updated 31 October 2024

What this trial tests

NA trial testing Angled guidewire in Bile Duct Diseases in 70 participants. Completed in 24 August 2023.

Timeline

22 October 2022

Primary endpoint
24 August 2023

24 August 2023

Quick facts

Lead sponsor	Neev Mehta
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	70
Start date	22 October 2022
Primary completion	24 August 2023
Estimated completion	24 August 2023
Sites	1 location across United States

Drugs / interventions tested

Angled guidewire
Straight guidewire

Conditions studied

Bile Duct Diseases — all drugs for Bile Duct Diseases →

Sponsor

Neev Mehta

Who can join

18 and older, any sex, with Bile Duct Diseases. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Cannulation Primary · Day of Procedure

Rate of successful cannulation of common bile duct

Group	Value	95% CI
Angled Wire	30
Straight Wire	31

Post ERCP Pancreatitis Secondary · Procedure day and up to day 5 post procedure

Number of participants who develop post ERCP pancreatitis

Group	Value	95% CI
Angled Wire	1
Straight Wire	2

Duration Secondary · Day of procedure

Total duration of procedure

Group	Value	95% CI
Angled Wire	1964.26	557 – 8520
Straight Wire	1569.03	711 – 4368

Adverse events — posted to ClinicalTrials.gov

Time frame: Randomization on day of procedure to post procedure day 5. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Angled Wire

Serious: 1/33 (3%)

Deaths: 0/33

Straight Wire

Serious: 2/33 (6%)

Deaths: 0/33

Serious adverse events (4 terms)

Reaction	System	Angled Wire	Straight Wire
post ERCP Pancreatitis	Gastrointestinal disorders	—	—
Perforation	Gastrointestinal disorders	—	—
Bleeding	Gastrointestinal disorders	—	—
Post ERCP Cholangitis	Infections and infestations	—	—

Most-reported serious reactions: post ERCP Pancreatitis, Perforation, Bleeding, Post ERCP Cholangitis.

Data from ClinicalTrials.gov NCT05600270 adverse events section.

Sponsor's own description

The investigators aim is to compare outcomes between an angled-tip guidewire and a straight-tip guidewire in cannulation of the common bile duct during ERCP. This is a randomized, controlled, single-blinded study. The primary outcome is success of cannulation and secondary outcomes are incidence of post-ERCP pancreatitis, procedure duration, and rate of complication between the angled wire and straight wire.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Bile Duct Diseases

Currently open trials in the same condition.

NCT07263061 — Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary Surgeries · recruiting
NCT06010576 — Endoscopic Ultrasound-guided Rendezvous Versus Precut Papillotomy · NA · recruiting
NCT05689255 — Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions · recruiting
NCT05014347 — Patient Reported Experience in Endoscopic Ultrasound · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05600270 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Neev Mehta
Last refreshed: 31 October 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05600270.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing