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NCT05599568
Repeated Bout Effect i Neuromuscular Diseases
NA trial testing Exercise in Myopathy in 50 participants. Currently enrolling.
1 January 2026
Quick facts
| Lead sponsor | Mads Peter Godtfeldt Stemmerik |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 50 |
| Start date | 15 May 2022 |
| Primary completion | 1 January 2026 |
| Estimated completion | 30 May 2026 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Exercise
Conditions studied
- Myopathy — all drugs for Myopathy →
Sponsor
Mads Peter Godtfeldt Stemmerik
Who can join
18 and older, any sex, with Myopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The repeated bout effect (RBE) refers to the adaptation whereby a single bout of eccentric exercise protects against muscle damage from subsequent eccentric bouts. This effect has been shown in many muscle groups using both serum biomarkers, muscle soreness and imaging techniques. Though the effect is well described in healthy, it has never been studied in patients with neuromuscular diseases (NMDs). In healthy, the RBE is only described using eccentric exercise, but unlike healthy persons, patients with NMDs can experience significant muscle damage with concentric exercise. This raises the question, if patients with NMDs could also show RBE when performing concentric exercise.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05599568
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Exercise
Trials testing the same drug.
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- NCT07589725 — Mulligan Mobilization in Lateral Elbow Tendinopathy · NA · not yet recruiting
- NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
- NCT06627569 — Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans · NA · not yet recruiting
Other recruiting trials for Myopathy
Currently open trials in the same condition.
- NCT04678635 — Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies · NA · recruiting
- NCT03749538 — Acute Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies · NA · recruiting
- NCT06374719 — WiTNNess - TNNT1 Myopathy Natural History Study · recruiting
- NCT03660969 — Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease · active not recruiting
Other Mads Peter Godtfeldt Stemmerik trials
Trials by the same sponsor.
- NCT04349566 — Fast Troponin as a Biomarker to Assess Exercise-induced Muscle Damage in Muscle Diseases · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05599568 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mads Peter Godtfeldt Stemmerik
- Last refreshed: 6 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05599568.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing