Last reviewed · How we verify
NCT05599035
Sleep Disorder in Parkinson Disease and rTMS
NA trial testing repititive transcranial magnetic stimulation in Sleep Disorder in 24 participants. Completed in 4 February 2024.
5 January 2024
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 24 |
| Start date | 2 May 2023 |
| Primary completion | 5 January 2024 |
| Estimated completion | 4 February 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- repititive transcranial magnetic stimulation
Conditions studied
- Sleep Disorder — all drugs for Sleep Disorder →
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
Assiut University
Who can join
Eligibility, any sex, with Sleep Disorder or Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The crude prevalence rate of Parkinson's disease in Upper Egypt governorates ranging from 557-436/100,000 (Assiut and Qena governorates respectively) which was one of the highest prevalence of PD around the world .Parkinson's disease patients report having complaints of disrupted sleep anywhere from 60 to 98 %. This is one of the most common non-motor symptoms, and it is a substantial contributor to the diminished quality of life associated with Parkinson's disease. PD patients have poor sleep maintenance and fragmentation (Comella 2007, Khedr et al. 2013). Khedr et al (2013) found that; 78.6% out of 112 patients with PD had sleep disturbances with the commonest complaint being difficulty getting to sleep at night or staying asleep (46.4%) followed by vivid nightmares and night terrors (27.7%). In other studies, 80-90% of PD patients have had sleep difficulty with virtually all patients having symptoms at some time in the course of the disease .
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Short-Term Therapeutic Effect of Repetitive Transcranial Magnetic Stimulations of Sleep Disorders in Parkinson’s Disease: A Randomized Clinical Trial (Pilot Study)
Khedr E, Ahmed G, Korayem M, Elamary S, et al · · 2024
Verify or expand the search:
- PubMed search for NCT05599035
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sleep Disorder
Currently open trials in the same condition.
- NCT07485790 — The Effects of Yoga on Pregnant Women · NA · recruiting
- NCT06990256 — Evaluation of Urolithin A and Fisetin on Improving Sleep and Aging Biomarkers · NA · recruiting
- NCT04949360 — SleepUp Digital CBTi-based Platform for Insomnia · NA · recruiting
- NCT05649514 — Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease · NA · recruiting
- NCT06914466 — Neural Mechanisms and Clinical Applications of DBS for Modulating Sleep Dysregulation in PD · recruiting
Other Assiut University trials
Trials by the same sponsor.
- NCT07423312 — Lead Exposure and Multiple Sclerosis · not yet recruiting
- NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05599035 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 2 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05599035.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing