Who is sponsoring NCT05596695?

NCT05596695 is sponsored by Medical University of Vienna.

What drugs are being tested in NCT05596695?

Interventions in NCT05596695: Minimizing blood pressure variability.

What condition does NCT05596695 study?

NCT05596695 studies PONV, Blood Pressure, Postoperative Recovery.

Is NCT05596695 still recruiting?

NCT05596695 is currently status unknown. Last updated 11 July 2023.

Last reviewed 2023-07-11 · How we verify

NCT05596695: SICK

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Minimisation of Blood Pressure Variability and Postoperative Nausea and Vomiting

Status unknown NA Last updated 11 July 2023

What this trial tests

NA trial testing Minimizing blood pressure variability in PONV in 272 participants. Status unknown.

Timeline

1 October 2022

Primary endpoint
1 October 2025

1 February 2026

Quick facts

Lead sponsor	Medical University of Vienna
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	272
Start date	1 October 2022
Primary completion	1 October 2025
Estimated completion	1 February 2026
Sites	1 location across Austria

Drugs / interventions tested

Minimizing blood pressure variability

Conditions studied

PONV — all drugs for PONV →
Blood Pressure — all drugs for Blood Pressure →
Postoperative Recovery — all drugs for Postoperative Recovery →

Sponsor

Medical University of Vienna

Who can join

Adults 18 to 50, female only, with PONV or Blood Pressure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intraoperative hypotension is associated with postoperative nausea and vomiting (PONV). Even though the exact mechanism linking PONV and hypotension is still unclear, a reduced intestinal tissue perfusion might trigger nausea and vomiting. Still to date only limited data evaluating intraoperative blood pressure and the incidence of PONV after general anesthesia exits. Furthermore, the effect of intraoperative blood pressure variability on the incidence of PONV has not been investigated yet. Therefore, we will test our primary hypothesis that the incidence of PONV during the early (0-2h) postoperative period will be minimized by targeting intraoperative blood pressure variability to a SPB of 120±5mmHg by using a continuous vasopressor infusion in female patients undergoing elective minor to moderate risk non-cardiac surgery.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for PONV

Currently open trials in the same condition.

NCT07515027 — Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung · NA · recruiting
NCT07176676 — Aromatherapy Treatment With Lavender Essential Oil to Reduce Post-Operative Nausea and Vomiting (PONV) · NA · active not recruiting
NCT07051109 — Dual-chamber Patient-controlled Analgesia for Postoperative Recovery · NA · recruiting
NCT03783182 — Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy · Phase 4 · recruiting
NCT03187535 — Effect of TEAS on PONV After Spinal Surgery · NA · recruiting

Other Medical University of Vienna trials

Trials by the same sponsor.

NCT07473401 — Retinal Oxygen Metabolism in Children With Myopia · not yet recruiting
NCT07511400 — The Role of NaV1.8 in Human Pain Models · EARLY_PHASE1 · not yet recruiting
NCT07516990 — Intramuscular Injection of Mashed Parathyroid Tissue Into a Forearm During Thyroid Surgery to Prevent Permanent Postoper · NA · recruiting
NCT07496437 — Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation? · NA · not yet recruiting
NCT07290712 — Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05596695 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of Vienna
Last refreshed: 11 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05596695.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing