NCT05595382

Motivations to Transplant Registry Participation

Completed NA Results posted Last updated 18 April 2025

What this trial tests

NA trial testing Emotional Appeal in Healthy in 397 participants. Completed in 6 November 2023.

Timeline

10 October 2022

Primary endpoint
6 November 2023

6 November 2023

Quick facts

Lead sponsor	Rutgers, The State University of New Jersey
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	health services research
Enrollment	397
Start date	10 October 2022
Primary completion	6 November 2023
Estimated completion	6 November 2023
Sites	1 location across United States

Drugs / interventions tested

• Emotional Appeal
• Rational Appeal

Conditions studied

• Healthy — all drugs for Healthy →

Sponsor

Rutgers, The State University of New Jersey

Who can join

Adults 18 to 35, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Intention to Register Primary · Baseline and after the experimental manipulation (Post-Intervention)

Participants rated the likelihood of registering on a 1-7 scale with higher scores indicating greater intention to join the registry (better outcome). Participants were asked these questions before (baseline) and after (post-intervention) the experimental manipulation.

Baseline

Group	Value	95% CI
Emotional Group	3.32	± .10
Rational Group	3.06	± .104

Post-Intervention

Group	Value	95% CI
Emotional Group	4.15	± 0.113
Rational Group	3.27	± 0.113

Mood Secondary · Baseline and after experimental manipulation (Post-Intervention)

Participant mood was assessed on a 1-10 scale, with higher scores indicating a better mood. Participants were asked these questions before (baseline) and after (post-intervention) the experimental manipulation.

Baseline

Group	Value	95% CI
Emotional Group	6.59	± .129
Rational Group	6.36	± .130

Post-Intervention

Group	Value	95% CI
Emotional Group	6.28	± .137
Rational Group	6.18	± .138

Psychosocial and Demographic Correlates of Intentions to Register--Knowledge Secondary · Baseline

Participants completed a knowledge measure about bone marrow and stem cell transplant donation using true/false statements about transplant donation that was examined as a correlate of their intentions to register with the transplant registry. The measure was scored as a percent of items answered correctly, higher scores indicating better knowledge.

Group	Value	95% CI
Emotional Group	19.5	± 18.0
Rational Group	22.6	± 18.0

Sponsor's own description

The current study seeks to understand factors that influence college students' likelihood of participating the National Marrow Donor Program (NMDP)/Be the Match for bone marrow and stem cell donations. The secondary aim is to compare emotional and rational approaches to encouraging participation in the registry and how these approaches may impact intentions to participate in the NMDP.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Increasing participation in the national marrow donor program: A randomized trial.
   Daniel LC, Elias G, Shah P, Kokolis N. · · 2026 · PMID 41015944 · DOI 10.1177/13591053251367869