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NCT05592821
Clinical and Radiographic Evaluation of Bone and Tissue Level Single Unit Implants: Two-piece Abutment Concept
trial testing dental implant placement in Bone Loss, Alveolar in 20 participants. Completed in 26 September 2023.
26 September 2022
Quick facts
| Lead sponsor | Berceste Guler |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 7 December 2020 |
| Primary completion | 26 September 2022 |
| Estimated completion | 26 September 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- dental implant placement
Conditions studied
- Bone Loss, Alveolar — all drugs for Bone Loss, Alveolar →
- Dental Implant Failed — all drugs for Dental Implant Failed →
Sponsor
Berceste Guler
Who can join
Adults 18 to 65, any sex, with Bone Loss, Alveolar or Dental Implant Failed. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dental implants have become one of the most common treatments used for the rehabilitation of lost teeth. The success rate of dental implant treatment is quite high. One of the criteria used for long-term implant success is the evaluation of radiographic marginal bone loss. Implants are used at the bone and tissue level in implant treatment. In this study, it was planned to use 20 implants of the same brand, with a single implant in the bilateral posterior regions in 10 patients.The study will be designed as split-mouth. The implant will be placed at the bone level with the same protocol in the two edentulous areas and the flap will be closed primarily. After 3 months, the substructure of the two-piece abutment concept system will be placed in a region during the healing head placement stage, and the bone level implant will be converted to the tissue level. A conventional healing cap will be placed in the other area. Periapical radiographs will be taken from the patients who participated in our study, as in all implant patients, during the pre-surgical planning phase and after implant placement. With the control periapical radiographs to be taken as a result of one-year follow-up, the marginal bone loss amount in the implants will be evaluated using soft-ware. Clinical measurements will be taken in all patients at the prosthetic loading session and 1 year after loading.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Effect of Two-Piece Abutment Concept and Abutment Reconnection/Disconnection on Marginal Bone Level Changes: A Split-Mouth Randomized, Parallel-Designed, 36-Month Follow-Up, Preliminary Clinical Study.
Ayyildiz BG, Terzioglu B, Bayindir BC. · · 2025 · PMID 40907027 · DOI 10.11607/jomi.11454
Verify or expand the search:
- PubMed search for NCT05592821
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of dental implant placement
Trials testing the same drug.
- NCT06794138 — The Success of Implant-borne Prostheses Following Fully-guided Static Computer-assisted Implant Surgery. · completed
- NCT06075017 — Biofilm Accumulation in Zirconia vs. Titanium Implants · NA · recruiting
- NCT05595746 — Radiological Bone Loss on Different Levels of Dental Implants · NA · completed
- NCT04308083 — The Influence of a New Implant Neck Configuration on Hard and Soft Tissue Healing · NA · unknown
- NCT07373548 — Long-Term Clinical and Radiographic Outcomes Following Freehand and Guided Dental Implant Placement: A Randomized Contro · NA · completed
Other recruiting trials for Bone Loss, Alveolar
Currently open trials in the same condition.
- NCT06653868 — Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts: Ra · NA · recruiting
- NCT06933030 — Assessment of Customized 3D Zirconium Versus Titanium Mesh for Anterior Maxillary Ridge Augmentation With Delayed Implan · NA · active not recruiting
- NCT06559605 — Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh · NA · recruiting
- NCT05602493 — A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Al · Phase 3 · active not recruiting
- NCT05610748 — Implant-supported Rehabilitation With SPAL Technique or Soft Tissue Augmentation · Phase 4 · active not recruiting
Other Berceste Guler trials
Trials by the same sponsor.
- NCT05604391 — The Effect of Free Gingival Graft on Root Closure · NA · recruiting
- NCT05591326 — The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession. · NA · enrolling by invitation
- NCT05618171 — Evaluation of the Patient's Risk Profile Using the Peri-implantitis Risk Diagram · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05592821 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Berceste Guler
- Last refreshed: 18 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05592821.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing