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NCT05592561
Impact of Supplements on Stress Markers
NA trial testing mental stress task in Physiological Stress in 109 participants. Completed in 10 April 2023.
10 April 2023
Quick facts
| Lead sponsor | Texas State University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 109 |
| Start date | 25 January 2022 |
| Primary completion | 10 April 2023 |
| Estimated completion | 10 April 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- mental stress task
Conditions studied
- Physiological Stress — all drugs for Physiological Stress →
Sponsor
Texas State University
Who can join
Adults 18 to 40, any sex, with Physiological Stress. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to examine the effects of caffeine, theanine and tyrosine ingestion on markers of stress in healthy college aged individuals that are exposed to a mental stress task. The main questions to answer are: 1. what is the impact of a mental stress task involving a cognitive challenge and virtual reality based active shooter scenario on markers of subjective and biological stress? 2. what is the impact of supplement ingestion (caffeine, theanine, tyrosine, analyzed separately) 40 min prior to exposure to the mental stress task?
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Stress response to virtual reality based active shooter training: Impact of caffeine consumption.
McAllister MJ, Martaindale MH, Dillard CC, Gonzalez DE. · · 2024 · cited 4× · PMID 38142605 · DOI 10.1016/j.psyneuen.2023.106923 -
Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill.
McAllister MJ, Martaindale MH, Dillard CC, McCullough R. · · 2024 · cited 1× · PMID 38975711 · DOI 10.1080/10253890.2024.2375588
Verify or expand the search:
- PubMed search for NCT05592561
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Texas State University trials
Trials by the same sponsor.
- NCT06986135 — The Effect of Breathing on Cognitive Performance and Stress · NA · completed
- NCT06680908 — Impact of Combined Stress on Biomarkers of Stress · completed
- NCT05815043 — Effects of Sodium Intake on Arterial Stiffness in Black Men and Women · NA · completed
- NCT05158205 — Yoga in Altering Mechanistic Outcomes in Hypertension · NA · terminated
- NCT05353270 — Effects of Yoga on Sodium-induced Pressor Responses in African American Adults · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05592561 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Texas State University
- Last refreshed: 12 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05592561.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing