NCT05591313 is a NA clinical trial of LI-40 in Alzheimer Disease 2 Due to Apoe4 Isoform, sponsored by National Taiwan Normal University.

Who is sponsoring NCT05591313?

NCT05591313 is sponsored by National Taiwan Normal University.

What drugs are being tested in NCT05591313?

Interventions in NCT05591313: LI-40, MI-30, HI-16.

What condition does NCT05591313 study?

NCT05591313 studies Alzheimer Disease 2 Due to Apoe4 Isoform.

Is NCT05591313 still recruiting?

NCT05591313 is currently completed. Last updated 8 February 2023.

Last reviewed 2023-02-08 · How we verify

NCT05591313

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Completed NA Last updated 8 February 2023

What this trial tests

NA trial testing LI-40 in Alzheimer Disease 2 Due to Apoe4 Isoform in 51 participants. Completed in 26 September 2019.

Timeline

17 May 2016

Primary endpoint
26 September 2019

26 September 2019

Quick facts

Lead sponsor	National Taiwan Normal University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	none
Primary purpose	treatment
Enrollment	51
Start date	17 May 2016
Primary completion	26 September 2019
Estimated completion	26 September 2019
Sites	1 location across Taiwan

Drugs / interventions tested

LI-40
MI-30
HI-16

Conditions studied

Alzheimer Disease 2 Due to Apoe4 Isoform — all drugs for Alzheimer Disease 2 Due to Apoe4 Isoform →

Sponsor

National Taiwan Normal University

Who can join

Adults 50 to 70, any sex, with Alzheimer Disease 2 Due to Apoe4 Isoform. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study explores the acute exercise effect on neurocognitive function and also its potential moderators in an exercise setting and Apolipoprotein E (APOE) genetic risk.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Acute Exercise Effect on Neurocognitive Function Among Cognitively Normal Late-Middle-Aged Adults With/Without Genetic Risk of AD: The Moderating Role of Exercise Volume and APOE Genotype.
Chang YK, Etnier JL, Li RH, Ren FF, et al · · 2024 · cited 6× · PMID 37526237 · DOI 10.1093/gerona/glad179

Verify or expand the search:

Other National Taiwan Normal University trials

Trials by the same sponsor.

NCT07501572 — Robot-Assisted Immersive Escape Room Game for Tobacco Harm Prevention Among Elementary School Students · NA · enrolling by invitation
NCT07095179 — Effects of Inspiratory Muscle Exercise on Health · NA · not yet recruiting
NCT07403864 — Effects of Acute Sleep Deprivation on Health · NA · not yet recruiting
NCT07393607 — Effects of Acute Sleep Deprivation on Human Behaviours · NA · not yet recruiting
NCT07444021 — Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05591313 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan Normal University
Last refreshed: 8 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05591313.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing