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NCT05590962

Predictive Analytics and Behavioral Nudges to Improve Palliative Care in Advanced Cancer

Completed NA Results posted Last updated 6 February 2025
What this trial tests

NA trial testing EHR Nudge in Cancer in 562 participants. Completed in 3 October 2023.

Timeline
9 November 2022
Primary endpoint
13 June 2023
3 October 2023

Quick facts

Lead sponsorAbramson Cancer Center at Penn Medicine
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposehealth services research
Enrollment562
Start date9 November 2022
Primary completion13 June 2023
Estimated completion3 October 2023
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Abramson Cancer Center at Penn Medicine — full company profile →

Who can join

18 and older, any sex, with Cancer. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Study Participants Who Have Completed a Palliative Care Visit Within 3 Months of Enrollment Primary · 3 months

Completed palliative care visit within 3 months among high-risk patients with stage III and IV lung and non-colorectal GI malignancies

GroupValue95% CI
Control22
Intervention130

Sponsor's own description

Patients with advanced cancer suffer from high symptom burden and aggressive end-of-life care. Early specialty palliative care is an evidence-based practice that improves symptom burden, quality of life, and survival in advanced cancer. However, over half of patients with advanced cancer die before receiving palliative care. Clinician-level biases and suboptimal identification of high-risk patients are major barriers to palliative care uptake. In this 2-arm pragmatic clinical trial, the investigators will randomize practices within a large community oncology network to receive an intervention consisting of algorithm-based default palliative care referrals. The investigators will study the impact of such an intervention on palliative care utilization and end-of-life outcomes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Algorithm-Based Palliative Care in Patients With Cancer: A Cluster Randomized Clinical Trial.
    Parikh RB, Ferrell WJ, Li Y, Chen J, et al · · 2025 · cited 4× · PMID 39982729 · DOI 10.1001/jamanetworkopen.2024.58576

Verify or expand the search:

Other recruiting trials for Cancer

Currently open trials in the same condition.

Other Abramson Cancer Center at Penn Medicine trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05590962.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing