Who is sponsoring NCT05588518?

NCT05588518 is sponsored by King Khalid University.

What drugs are being tested in NCT05588518?

Interventions in NCT05588518: desensitizing agents -10% Propolis.

What condition does NCT05588518 study?

NCT05588518 studies Dental Root Sensitivity.

Is NCT05588518 still recruiting?

NCT05588518 is currently completed. Last updated 20 October 2022.

Last reviewed 2022-10-20 · How we verify

NCT05588518

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Propolis as a Treatment for Cervical Dentin Hypersensitivity

Completed NA Last updated 20 October 2022

What this trial tests

NA trial testing desensitizing agents -10% Propolis in Dental Root Sensitivity in 75 participants. Completed in 1 August 2020.

Timeline

1 April 2019

Primary endpoint
1 February 2020

1 August 2020

Quick facts

Lead sponsor	King Khalid University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	75
Start date	1 April 2019
Primary completion	1 February 2020
Estimated completion	1 August 2020
Sites	1 location across Saudi Arabia

Drugs / interventions tested

desensitizing agents -10% Propolis

Conditions studied

Dental Root Sensitivity — all drugs for Dental Root Sensitivity →

Sponsor

King Khalid University

Who can join

Adults 25 to 60, any sex, with Dental Root Sensitivity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Fluoridated desensitizers the frequently used for the treatment of dentin hypersensitivity (DH) with Iontophoresis. This study aimed to evaluate and compare the immediate and long-term effects of 10% Propolis with 2% sodium fluoride and 1.23% acidulated phosphate fluoride when applied along with Iontophoresis for the treatment of cervical dentin hypersensitivity (DH). Single-center, parallel, and double-blinded randomized clinical trials were conducted on systemically healthy patients, complaining about DH, with at least two sites. 10% propolis, 2% Sodium Fluoride and 1.23% Acidulated Phosphate Fluoride were used as desensitizers along with the Iontophoresis. After applying specific stimuli any decrease in DH was measured at baseline before and after application, on the 14th day after use, and at 28th-day post-intervention time intervals.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Propolis and Their Active Constituents for Chronic Diseases.
Chavda VP, Chaudhari AZ, Teli D, Balar P, et al · · 2023 · cited 18× · PMID 36830794 · DOI 10.3390/biomedicines11020259
Evaluation of Propolis Hydrogel for the Treatment of Dentinal Sensitivity: A Clinical Study.
AlQahtani SM, Nagate RR, Al-Ahmari MMM, Magbol MA, et al · · 2023 · cited 3× · PMID 37367153 · DOI 10.3390/gels9060483

Verify or expand the search:

Other King Khalid University trials

Trials by the same sponsor.

NCT06774196 — Integrating Behavioral Therapy in the Management of Temporomandibular Disorders: A Comprehensive Evaluation Using DC/TMD · NA · completed
NCT06948682 — Exploring the Relationship Between Occlusion and Degenerative TMJ Disorders: A Comparative Clinical Study · NA · completed
NCT07396610 — Effect of Diode Laser and Bioactive Glass on Dentinal Hypersensitivity · NA · completed
NCT06758479 — Differential Impact of TMJ Disc Displacement and Muscle Disorders on Pain, Function, and Quality of Life in TMD Patients · completed
NCT06280651 — Dietary Impacts on Oral Health in Autistic Children: A Cross-Sectional Analysis · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05588518 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by King Khalid University
Last refreshed: 20 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05588518.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing