NCT05586373 (DIPROFEN) is a Phase 4 clinical trial of medication 1 in Preeclampsia, sponsored by Instituto Materno Infantil Prof. Fernando Figueira.

Who is sponsoring NCT05586373?

NCT05586373 is sponsored by Instituto Materno Infantil Prof. Fernando Figueira.

What drugs are being tested in NCT05586373?

Interventions in NCT05586373: medication 1, medication 2.

What condition does NCT05586373 study?

NCT05586373 studies Preeclampsia.

Is NCT05586373 still recruiting?

NCT05586373 is currently completed. Last updated 9 June 2023.

Last reviewed 2023-06-09 · How we verify

NCT05586373: DIPROFEN

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ibuprofen vs Dipyrone After C-section in Preeclampsia

Completed Phase 4 Last updated 9 June 2023

What this trial tests

Phase 4 trial testing medication 1 in Preeclampsia in 74 participants. Completed in 31 May 2023.

Timeline

15 October 2022

Primary endpoint
31 May 2023

31 May 2023

Quick facts

Lead sponsor	Instituto Materno Infantil Prof. Fernando Figueira
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	74
Start date	15 October 2022
Primary completion	31 May 2023
Estimated completion	31 May 2023
Sites	1 location across Brazil

Drugs / interventions tested

medication 1 — full drug profile →
medication 2 — full drug profile →

Conditions studied

Preeclampsia — all drugs for Preeclampsia →

Sponsor

Instituto Materno Infantil Prof. Fernando Figueira

Who can join

14 and older, female only, with Preeclampsia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this randomized, triple-masked clinical trial is to compare the effectiveness and safety of the use of ibuprofen versus dipyrone for postoperative analgesia in postpartum women with preeclampsia undergoing cesarean section. The main question it aims to answer are: * Postoperative pain is similar; * The frequency of acute kidney injury is similar. Researchers will compare one group that will receive dipyrone and the other group that will receive ibuprofen to see if Postoperative pain are different between groups or development of acute kidney injury each group is different.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Preeclampsia

Currently open trials in the same condition.

NCT06953115 — Vagal Stimulation Therapy and Preeclampsia · NA · recruiting
NCT06333652 — Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders · Phase 2 · recruiting
NCT07282171 — A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Parti · Phase 1 · recruiting
NCT07345845 — MR and Inflammation After Preeclampsia · EARLY_PHASE1 · active not recruiting
NCT07041281 — Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories · Phase 2 · recruiting

Other Instituto Materno Infantil Prof. Fernando Figueira trials

Trials by the same sponsor.

NCT07480083 — Low-level Laser Therapy in Pain and Perineal Healing in the Immediate Postpartum Period: a Randomized Clinical Trial. · NA · not yet recruiting
NCT05590481 — Effect of Tibial Transcutaneous Electrostimulation in Women with Urgency Urinary Incontinence · NA · completed
NCT06601582 — Effectiveness of a Intraoperative Blood Recovery System in Cardiovascular Surgery in Brazil · NA · recruiting
NCT04462367 — Northeast COVID-19 and Pregnancy Study Group · unknown
NCT04124835 — Effectiveness of Using the Swiss Ball in Birth · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05586373 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Instituto Materno Infantil Prof. Fernando Figueira
Last refreshed: 9 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05586373.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing