NCT05585931 is a Phase 1 clinical trial of TPN171H 10mg in Erectile Dysfunction, sponsored by Vigonvita Life Sciences.

Who is sponsoring NCT05585931?

NCT05585931 is sponsored by Vigonvita Life Sciences.

What drugs are being tested in NCT05585931?

Interventions in NCT05585931: TPN171H 10mg, TPN171H Placebo.

What condition does NCT05585931 study?

NCT05585931 studies Erectile Dysfunction.

Is NCT05585931 still recruiting?

NCT05585931 is currently completed. Last updated 21 February 2023.

Last reviewed 2023-02-21 · How we verify

NCT05585931

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of TPN171H on Spermatogenesis

Completed Phase 1 Last updated 21 February 2023

What this trial tests

Phase 1 trial testing TPN171H 10mg in Erectile Dysfunction in 18 participants. Completed in 16 December 2022.

Timeline

15 November 2022

Primary endpoint
16 December 2022

16 December 2022

Quick facts

Lead sponsor	Vigonvita Life Sciences
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	treatment
Enrollment	18
Start date	15 November 2022
Primary completion	16 December 2022
Estimated completion	16 December 2022
Sites	1 location across China

Drugs / interventions tested

TPN171H 10mg
TPN171H Placebo

Conditions studied

Erectile Dysfunction — all drugs for Erectile Dysfunction →

Sponsor

Vigonvita Life Sciences — full company profile →

Who can join

Adults 18 to 40, male only, with Erectile Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a phaseⅠstudy to determine the acute effects of TPN171H on semen function in healthy male subjects.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of the acute effects of single-dose TPN171 on semen quality in healthy Chinese male volunteers.
Yang Y, Zhang Z, Li L, Jiang Z, et al · · 2025 · PMID 40181588 · DOI 10.1002/bcp.70049

Verify or expand the search:

Other trials of TPN171H 10mg

Trials testing the same drug.

NCT05388825 — Pharmacodynamic Study of TPN171H Tablets in Patients With Mild to Moderate Erectile Dysfunction · Phase 2 · completed

Other recruiting trials for Erectile Dysfunction

Currently open trials in the same condition.

NCT07442396 — The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation · NA · recruiting
NCT07366970 — Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D? · NA · recruiting
NCT06960746 — Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response? · NA · recruiting
NCT06872866 — The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under · Phase 1 · recruiting
NCT06805513 — Actual Use Trial of Tadalafil 5 mg · Phase 3 · recruiting

Other Vigonvita Life Sciences trials

Trials by the same sponsor.

NCT07507838 — Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV913 Capsules · EARLY_PHASE1 · not yet recruiting
NCT07302269 — Study of the Safety, Tolerability, Pharmacokinetics of VV261 Tablets in Chinese Healthy Volunteers · Phase 1 · recruiting
NCT06749236 — A Study to Evaluate the Bioavailability of Two Specifications of Oral Deuremidevir Hydrobromide for Suspension · Phase 1 · completed
NCT06828887 — Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD · Phase 2 · recruiting
NCT06504290 — Evaluating Safety, Tolerability and Pharmacokinetic of Multiple Ascending Doses of VV119 · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05585931 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vigonvita Life Sciences
Last refreshed: 21 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05585931.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing