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NCT05579678: APOLLO

APOLLO: Personalized rehAbilitation PrOgram in aLLOgeneic Bone Marrow Transplantation

Recruiting now Last updated 19 September 2024
What this trial tests

trial testing Supportive nursing, nutritional and physical activity with a handheld 'app' in Allogeneic Disease in 45 participants. Currently enrolling.

Timeline
20 November 2022
Primary endpoint
30 June 2025
30 June 2025

Quick facts

Lead sponsorUniversity of Alberta
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment45
Start date20 November 2022
Primary completion30 June 2025
Estimated completion30 June 2025
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

University of Alberta

Who can join

Adults 18 to 70, any sex, with Allogeneic Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

People who undergo allogeneic bone marrow transplant for blood cancers receive the highest chemotherapy doses possible that humans can receive and still survive. As a result, they have devastating side effects during the procedure and for many years afterwards. Damage to organs and muscles cause long-lasting physical weakness and the psychological experience is severe enough to be termed 'post traumatic stress disorder' that also lasts for many years. These effects are worsened by the fact that most Canadians live several hours away from treatment and transplant centers, leaving them entirely on their own to manage these difficult long term effects. The APOLLO team will perform a qualitative study to learn the experiences of people undergoing allogeneic bone marrow transplant while they receive access to a supportive care computer 'app' and telephone support from nursing, exercise and nutrition experts. In this way, the APOLLO team will learn the most helpful type and timing of supportive care from those who know best.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation.
    Pituskin E, Foulkes S, Skow RJ, McMurtry T, et al · · 2025 · PMID 39875816 · DOI 10.1186/s12885-025-13502-8

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