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NCT05578105

Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan

Recruiting now Last updated 13 October 2022
What this trial tests

trial testing no intervention in Autoimmune Polyendocrine Syndrome Type II in 650 participants. Currently enrolling.

Timeline
1 January 2022
Primary endpoint
31 December 2026
31 December 2026

Quick facts

Lead sponsorNational Taiwan University Hospital
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment650
Start date1 January 2022
Primary completion31 December 2026
Estimated completion31 December 2026
Sites1 location across Taiwan

Drugs / interventions tested

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

20 and older, any sex, with Autoimmune Polyendocrine Syndrome Type II. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. A 20-year study of autoimmune polyendocrine syndrome type II and III in Taiwan.
    Tseng HH, Lin YB, Lin KY, Lin CH, et al · · 2023 · cited 2× · PMID 37878416 · DOI 10.1530/etj-23-0162

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