NCT05577741: ENVELMIND

Effect of the Enriched Environment on the Risk of Relapse

Completed NA Last updated 13 January 2026

What this trial tests

NA trial testing Multisensory virtual reality pod (SENSIKS©) in Alcoholic Relapse in 135 participants. Completed in 9 July 2025.

Timeline

29 November 2022

Primary endpoint
9 July 2025

9 July 2025

Quick facts

Lead sponsor	Centre Hospitalier Henri Laborit
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	135
Start date	29 November 2022
Primary completion	9 July 2025
Estimated completion	9 July 2025
Sites	1 location across France

Drugs / interventions tested

• Multisensory virtual reality pod (SENSIKS©)
• Cognitive bike (Vélo-cognitif®)
• Standard treatment

Conditions studied

• Alcoholic Relapse — all drugs for Alcoholic Relapse →

Sponsor

Centre Hospitalier Henri Laborit

Who can join

Adults 18 to 65, any sex, with Alcoholic Relapse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This clinical study investigates the effects of enriched environment on the risk of relapse in alcoholic patients.

135 patients hospitalized for an alcoholic addiction will be recruited and randomized in two groups: one group will receive standard of care, the other group will receive a treatment with enriched environment.

The enriched environment consists of six sessions of virtual reality (20 minutes) in a multi-sensory pod and six sessions (20 minutes) of bike activity with cognitive tasks while pedalling.

The multi-sensory virtual reality pod allows mindfulness practice and allows patients to be in immersive situations that may trigger cues in order to help them in craving management.

The bike consists in the combination of a pedal set and a touch pad on which cognitive training games are offered. This tool thus makes it possible to simultaneously stimulate motor skills and cognition by means of bicycle-game coupling.

Patients are then followed during 3 months and a half.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effect of environmental enrichment on relapse rates in patients with severe alcohol use disorder: protocol for a randomised controlled trial.
   Barillot L, Chauvet C, Besnier M, Jaafari N, et al · · 2023 · cited 5× · PMID 37173113 · DOI 10.1136/bmjopen-2022-069249