NCT05575427 is a Phase 4 clinical trial of Minocycline in Hospital Infections, sponsored by Mahidol University.

Who is sponsoring NCT05575427?

NCT05575427 is sponsored by Mahidol University.

What drugs are being tested in NCT05575427?

Interventions in NCT05575427: Minocycline, Levofloxacin or Cotrimoxazole, Placebo.

What condition does NCT05575427 study?

NCT05575427 studies Hospital Infections.

Is NCT05575427 still recruiting?

NCT05575427 is currently status unknown. Last updated 10 January 2023.

Last reviewed 2023-01-10 · How we verify

NCT05575427

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Combination Therapy With Minocycline for Treatment of Stenotrophomonas Maltophilia Infections

Status unknown Phase 4 Last updated 10 January 2023

What this trial tests

Phase 4 trial testing Minocycline in Hospital Infections in 112 participants. Status unknown.

Timeline

24 November 2022

Primary endpoint
1 July 2024

1 November 2024

Quick facts

Lead sponsor	Mahidol University
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	112
Start date	24 November 2022
Primary completion	1 July 2024
Estimated completion	1 November 2024
Sites	1 location across Thailand

Drugs / interventions tested

Minocycline (MINOCYCLINE) — full drug profile →
Levofloxacin or Cotrimoxazole — full drug profile →
Placebo

Conditions studied

Hospital Infections — all drugs for Hospital Infections →

Sponsor

Mahidol University

Who can join

Adults 18 to 95, any sex, with Hospital Infections. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of the study is to evaluate the efficacy of minocycline for treatment Stenotrophomonas maltophilia infection. The hypothesis of study is the combination therapy with minocycline would be better than the monotherapy for treatment Stenotrophomonas maltophilia infection.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Editorial for the Special Issue: "The Issue of Multidrug-Resistant Pathogens in Nosocomial Infections".
Maraolo AE. · · 2023 · PMID 38136717 · DOI 10.3390/antibiotics12121683

Verify or expand the search:

Other trials of Minocycline

Trials testing the same drug.

NCT05605366 — Minocycline In Neurocognitive Outcomes - Sickle Cell Disease · Phase 1 · not yet recruiting
NCT07305896 — Efficacy and Safety of Minocycline in the Treatment of Intracerebral Hemorrhage · NA · not yet recruiting
NCT07068607 — Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradicatio · Phase 4 · recruiting
NCT06523764 — Efficacy and Safety of Tegoprazan and Minocycline Dual Therapy for Helicobacter Pylori Initial Treatment · Phase 4 · active not recruiting
NCT06120140 — Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small · Phase 2 · recruiting

Other Mahidol University trials

Trials by the same sponsor.

NCT07568496 — Greater Occipital Nerve Block for Migraine With Medication Overuse Headache · NA · not yet recruiting
NCT07407400 — Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients · Phase 4 · not yet recruiting
NCT07378501 — Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study · not yet recruiting
NCT07438301 — Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration · not yet recruiting
NCT07390006 — Enabling Patient-Reported Outcomes Through Innovative Care - ACS (EPIC-ACS) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05575427 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mahidol University
Last refreshed: 10 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05575427.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing