Last reviewed · How we verify
NCT05574647: IP7-PACIFIC
Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer
NA trial testing bpMRI in Prostate Cancer in 3,600 participants. Currently enrolling.
31 October 2025
Quick facts
| Lead sponsor | Imperial College London |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 3,600 |
| Start date | 2 November 2022 |
| Primary completion | 31 October 2025 |
| Estimated completion | 31 January 2026 |
| Sites | 15 locations across United Kingdom |
Drugs / interventions tested
- bpMRI
- Image-Fusion targeted and systematic Biopsy
Conditions studied
- Prostate Cancer — all drugs for Prostate Cancer →
- Adenocarcinoma — all drugs for Adenocarcinoma →
- Prostatic Neoplasms — all drugs for Prostatic Neoplasms →
- Prostatic Diseases — all drugs for Prostatic Diseases →
Sponsor
Imperial College London
Who can join
18 and older, male only, with Prostate Cancer or Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the role of biparametric MRI and image-fusion targeted biopsies for the detection of prostate cancer. To determine whether biparametric MRI (bpMRI) could be recommended as an alternative to multiparametric MRI (mpMRI) for the detection of clinically significant prostate cancers in patients at risk. To determine whether image-fusion targeted biopsy is better than visual-registration (cognitive) targeted biopsy at detecting clinically significant prostate cancers in patients requiring prostate biopsy due to a suspicious MRI.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Contrast-medium administration for prostate MRI: yes! Contrast-medium administration can be abandoned.
Asbach P. · · 2023 · cited 3× · PMID 37420101 · DOI 10.1007/s00330-023-09766-y
Verify or expand the search:
- PubMed search for NCT05574647
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05574647 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Imperial College London
- Last refreshed: 24 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05574647.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing