NCT05574088 is a NA clinical trial of Apical patency with file in Pain, Postoperative, sponsored by Prime Foundation.

Who is sponsoring NCT05574088?

NCT05574088 is sponsored by Prime Foundation.

What drugs are being tested in NCT05574088?

Interventions in NCT05574088: Apical patency with file.

What condition does NCT05574088 study?

NCT05574088 studies Pain, Postoperative, Acute Pain.

Is NCT05574088 still recruiting?

NCT05574088 is currently completed. Last updated 29 March 2023.

Last reviewed 2023-03-29 · How we verify

NCT05574088

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Postoperative Pain With or Without Apical Patency Technique in Asymptomatic Necrotic Teeth

Completed NA Last updated 29 March 2023

What this trial tests

NA trial testing Apical patency with file in Pain, Postoperative in 60 participants. Completed in 30 November 2022.

Timeline

1 September 2022

Primary endpoint
25 October 2022

30 November 2022

Quick facts

Lead sponsor	Prime Foundation
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	60
Start date	1 September 2022
Primary completion	25 October 2022
Estimated completion	30 November 2022
Sites	1 location across Pakistan

Drugs / interventions tested

Apical patency with file

Conditions studied

Pain, Postoperative — all drugs for Pain, Postoperative →
Acute Pain — all drugs for Acute Pain →

Sponsor

Prime Foundation

Who can join

Adults 18 to 60, any sex, with Pain, Postoperative or Acute Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Apical patency is a technique in which the apical portion of the canal is maintained free of soft tissue remnants and dentinal debris by recapitulation with a small #10k file through the apical foramen. The purpose of this study is to evaluate the association between apical patency and postoperative pain in teeth with asymptomatic necrotic pulp among patients attending the Peshawar Dental College and Hospital. This single center, double blinded prospective RCT study will be conducted in Peshawar Dental College and Hospital. The inclusion criteria will be mature maxillary and mandibular molars and premolars diagnosed with asymptomatic necrotic pulp and apical periodontitis among 18-60 aged male and female patients, whereas pregnant patients, individuals with previously accessed teeth, and those having positive history of analgesic use within past 3 days will be excluded from the study. A total of 60 patients, after an informed consent will be randomly allocated one of the two groups i.e., apical patency (AP)(n = 30) and the non-apical patency (NAP) (n = 30) in a ratio (1:1).After administering localanaesthesia, root canal preparation will be completed using ProTaper rotary instruments.A size 10 K-filewas carried 1 mm beyond the working length in the patency groupused as a patency file.Patients will be asked to mark their pain intensity on 0-10 scale (NRS)for 7 days. Data will be analyzed using ChiSquare test, Student t-test, Kolmogorov-Smirnov test.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other Prime Foundation trials

Trials by the same sponsor.

NCT07303478 — Comparison of Obturation Quality and Lateral Canal Fill (by Sealer): Ultrasonic-Activated Versus Non-Ultrasonic Conventi · NA · not yet recruiting
NCT07253025 — Comparison of Post Operative Pain in Resin-Based and Bioceramic Based Root Canal Sealers in Patient Presenting at Peshaw · NA · recruiting
NCT06333730 — Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teet · NA · unknown
NCT05895526 — Comparison of the Effectiveness of Self Etch Adhesive and Fluoride Varnish in Reducing Hypersensitivity in Patients With · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05574088 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Prime Foundation
Last refreshed: 29 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05574088.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing