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NCT05573529
EDOF and Multifocal IOL Study
NA trial testing phacoemulsification and intraocular lens implantation in Age-related Cataract in 50 participants. Completed in 5 February 2025.
23 March 2023
Quick facts
| Lead sponsor | Medical University of Vienna |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 9 November 2020 |
| Primary completion | 23 March 2023 |
| Estimated completion | 5 February 2025 |
| Sites | 1 location across Austria |
Drugs / interventions tested
- phacoemulsification and intraocular lens implantation
- intraocular lens implantation
Conditions studied
- Age-related Cataract — all drugs for Age-related Cataract →
Sponsor
Medical University of Vienna
Who can join
Adults 50 to 90, any sex, with Age-related Cataract. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. Cataract surgery with precedent bilateral randomized IOL implantation will be performed in subjects who have signed an informed consent form. Postoperative examinations will be implemented in accordance with the approved investigational plan.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical prospective intra-individual comparison after mix-and-match implantation of a monofocal EDOF and a diffractive trifocal IOL.
Danzinger V, Schartmüller D, Schwarzenbacher L, Röggla V, et al · · 2024 · cited 11× · PMID 37524833 · DOI 10.1038/s41433-023-02682-x -
Three-year comparison of two mix-and-match strategies: enhanced monofocal and trifocal vs enhanced monofocal and trifocal EDOF intraocular lenses.
Danzinger V, Lisy M, Schartmüller D, Mahnert N, et al · · 2026 · cited 1× · PMID 41105092 · DOI 10.1097/j.jcrs.0000000000001808
Verify or expand the search:
- PubMed search for NCT05573529
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of phacoemulsification and intraocular lens implantation
Trials testing the same drug.
- NCT05822089 — Intraindividual Comparison of EMO IOLs · NA · recruiting
Other Medical University of Vienna trials
Trials by the same sponsor.
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- NCT07516990 — Intramuscular Injection of Mashed Parathyroid Tissue Into a Forearm During Thyroid Surgery to Prevent Permanent Postoper · NA · recruiting
- NCT07496437 — Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation? · NA · not yet recruiting
- NCT07290712 — Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05573529 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of Vienna
- Last refreshed: 18 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05573529.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing