Who is sponsoring NCT05573178?

NCT05573178 is sponsored by China National Center for Cardiovascular Diseases.

What drugs are being tested in NCT05573178?

Interventions in NCT05573178: cardiac ganglion plexus ablation(cardioneuroablation).

What condition does NCT05573178 study?

NCT05573178 studies Syncope, Vasovagal.

Is NCT05573178 still recruiting?

NCT05573178 is currently completed. Last updated 1 December 2023.

Last reviewed 2023-12-01 · How we verify

NCT05573178

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Different Catheter Ablation Strategy in Vasovagal Syncope

Completed NA Last updated 1 December 2023

What this trial tests

NA trial testing cardiac ganglion plexus ablation(cardioneuroablation) in Syncope, Vasovagal in 80 participants. Completed in 30 November 2023.

Timeline

26 December 2020

Primary endpoint
20 November 2023

30 November 2023

Quick facts

Lead sponsor	China National Center for Cardiovascular Diseases
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	80
Start date	26 December 2020
Primary completion	20 November 2023
Estimated completion	30 November 2023
Sites	2 locations across China

Drugs / interventions tested

cardiac ganglion plexus ablation(cardioneuroablation)

Conditions studied

Syncope, Vasovagal — all drugs for Syncope, Vasovagal →

Sponsor

China National Center for Cardiovascular Diseases — full company profile →

Who can join

Eligibility, any sex, with Syncope, Vasovagal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a prospective, single-center randomized controlled clinical trial. patients with refractory vasovagal syncope were randomly divided into two groups according to the proportion of 1:1. Group A: simple left atrial ganglion plexus ablation (RAGP + LSGP + LLGP + LIGP + RIGP ablation); B group: left atrial ganglion plexus combined with right atrial ganglion plexus ablation (group A + consolidation ablation of RAGP at the junction of right atrial septum and superior vena cava). To clarify the role of RAGP in cardiac autonomic nervous system and the effect of ablation, to establish the standard stragtegy of cardiac nerve ablation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Efficacy of Left Atrial vs Biatrial Cardioneuroablation in Patients With Vasovagal Syncope: A Randomized Clinical Trial.
Tu B, Chen A, Cai S, Zhang Z, et al · · 2025 · cited 5× · PMID 40117421 · DOI 10.1016/j.jacep.2025.01.019

Verify or expand the search:

Other trials of cardiac ganglion plexus ablation(cardioneuroablation)

Trials testing the same drug.

NCT04149886 — Cardiac Ganglionated Plexus Ablation Before Permanent Pacemaker Implantation in Patients With Sick Sinus Syndrome · NA · unknown

Other recruiting trials for Syncope, Vasovagal

Currently open trials in the same condition.

NCT06159764 — National Registry of Cardioneuroablation in Recurrent Reflex Syncope · recruiting
NCT06496074 — Heart Rate Variation in Females Predicts Tilt Test Results · active not recruiting
NCT06472102 — Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography · NA · recruiting
NCT06458140 — Cardioneuroablation and Ventricular Proarrhythmia · NA · recruiting
NCT06440291 — Cardioneuroablation for Reflex Syncope and Exercise Capacity · NA · recruiting

Other China National Center for Cardiovascular Diseases trials

Trials by the same sponsor.

NCT07514988 — Sirolimus-Coated vs Paclitaxel-Coated DCBs in ACS Treatment · NA · not yet recruiting
NCT07476456 — Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death · not yet recruiting
NCT07302659 — Aortic No-Touch vs Partial Aortic Clamping in Off-Pump CABG · NA · recruiting
NCT07482683 — Predicting Post-Cardiac Surgery Acute Kidney Disease: A Machine Learning Approach · not yet recruiting
NCT06787430 — Effects of Nicorandil on Microvascular Dysfunction in Patients With STEMI Undergoing Primary PCI · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05573178 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by China National Center for Cardiovascular Diseases
Last refreshed: 1 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05573178.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing