NCT05572190 is a Phase 1 clinical trial of ETR028, ETR029, [ETR028 + ETR029] or HCBT in Acute Pain, sponsored by Elysium Therapeutics, Inc..

Who is sponsoring NCT05572190?

NCT05572190 is sponsored by Elysium Therapeutics, Inc..

What drugs are being tested in NCT05572190?

Interventions in NCT05572190: ETR028, ETR029, [ETR028 + ETR029] or HCBT.

What condition does NCT05572190 study?

NCT05572190 studies Acute Pain.

Is NCT05572190 still recruiting?

NCT05572190 is currently status unknown. Last updated 13 September 2023.

Last reviewed 2023-09-13 · How we verify

NCT05572190

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluate the Safety and Pharmacokinetic Profile of ETR028 and ETR029 in Healthy Adult Subjects

Status unknown Phase 1 Last updated 13 September 2023

What this trial tests

Phase 1 trial testing ETR028, ETR029, [ETR028 + ETR029] or HCBT in Acute Pain in 78 participants. Status unknown.

Timeline

27 September 2022

Primary endpoint
20 March 2024

31 March 2024

Quick facts

Lead sponsor	Elysium Therapeutics, Inc.
Phase	Phase 1
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	78
Start date	27 September 2022
Primary completion	20 March 2024
Estimated completion	31 March 2024
Sites	1 location across United States

Drugs / interventions tested

ETR028, ETR029, [ETR028 + ETR029] or HCBT — full drug profile →

Conditions studied

Acute Pain — all drugs for Acute Pain →

Sponsor

Elysium Therapeutics, Inc. — full company profile →

Who can join

Adults 18 to 55, any sex, with Acute Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this Phase 1 clinical study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of O2P (Oral Overdose Protected) hydrocodone prodrugs (ETR028 and ETR029) relative to hydrocodone bitartrate hemipentahydrate (HCBT) comparator following single oral doses in healthy adult subjects under fasted and fed conditions with naltrexone blockade

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Acute Pain

Currently open trials in the same condition.

NCT06779604 — Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery · recruiting
NCT07348419 — Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery · NA · recruiting
NCT07335159 — Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention · NA · recruiting
NCT07348523 — Comparison of the Postoperative Analgesic Efficacy of Classical and Modified Erector Spinae Plane Blocks After Lumbar Sp · NA · recruiting
NCT07336264 — Characterization of Acute Pain · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05572190 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Elysium Therapeutics, Inc.
Last refreshed: 13 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05572190.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing