Last reviewed · How we verify
NCT05570240
The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients.
trial in Knee Osteoarthritis in 60 participants. Completed in 22 April 2021.
21 April 2021
Quick facts
| Lead sponsor | Kaohsiung Veterans General Hospital. |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 7 August 2019 |
| Primary completion | 21 April 2021 |
| Estimated completion | 22 April 2021 |
| Sites | 1 location across Taiwan |
Conditions studied
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Neuroinflammatory Response — all drugs for Neuroinflammatory Response →
Sponsor
Kaohsiung Veterans General Hospital.
Who can join
Adults 20 to 86, any sex, with Knee Osteoarthritis or Neuroinflammatory Response. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to learn about the association between pain characteristics and cognitive functions in chronic knee osteoarthritis. The main questions it aims to answer are: 1. If pain characteristics affect cognitive functions in severe knee OA patients? 2. If concentration of neuroinflammation mediators were raised in severe knee OA patients with comparing with control group participants? Participants will receive pain and cognition questionnaire before surgery and their blood and CSF will be collected for further analysis of neuroinflammation mediators.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Brain Amyloid-β Peptide Is Associated with Pain Intensity and Cognitive Dysfunction in Osteoarthritic Patients.
Wen CH, Kang HY, Chan JYH. · · 2024 · cited 1× · PMID 39684287 · DOI 10.3390/ijms252312575
Verify or expand the search:
- PubMed search for NCT05570240
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Kaohsiung Veterans General Hospital. trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05570240 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kaohsiung Veterans General Hospital.
- Last refreshed: 6 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05570240.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing