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NCT05565430
Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics.
trial testing Acute Hyperventilation in Hyperventilation in 24 participants. Completed in 10 February 2025.
10 February 2025
Quick facts
| Lead sponsor | Monash Medical Centre |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 24 |
| Start date | 1 June 2018 |
| Primary completion | 10 February 2025 |
| Estimated completion | 10 February 2025 |
| Sites | 1 location across Australia |
Drugs / interventions tested
- Acute Hyperventilation
- Chronic hyperventilation
- Effects of anticholinergic medication — full drug profile →
Conditions studied
- Hyperventilation — all drugs for Hyperventilation →
- Larynx — all drugs for Larynx →
- Asthma — all drugs for Asthma →
Sponsor
Monash Medical Centre — full company profile →
Who can join
Adults 18 to 65, any sex, with Hyperventilation or Larynx. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Investigators aim to: 1. Study the effect of hyperventilation on the development of paradoxical vocal cord movement (PVCM) in healthy individuals and in patients with mild and severe asthma, 2. Relate PVCM to airway symptoms and measurements of intra- and extra-thoracic airway hyperresponsiveness (ET-AHR), 3. Evaluate the effects of inhaled anti-cholinergic agents on PVCM induced by hyperventilation. Hypotheses: 1. In health PVCM will not occur in response to hyperventilation, 2. In asthma PVCM will occur in response to hyperventilation, 3. Airway symptoms and ET-AHR will develop in parallel with PVCM, 4. Inhaled anticholinergic agents will prevent PVCM induced by hyperventilation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05565430
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Related trials
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05565430 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Monash Medical Centre
- Last refreshed: 8 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05565430.
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