Who is sponsoring NCT05557461?

NCT05557461 is sponsored by Bozyaka Training and Research Hospital.

What condition does NCT05557461 study?

NCT05557461 studies Septic Shock, Hypovolemia, Sepsis.

Is NCT05557461 still recruiting?

NCT05557461 is currently status unknown. Last updated 25 January 2023.

Last reviewed 2023-01-25 · How we verify

NCT05557461

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?

Status unknown Last updated 25 January 2023

What this trial tests

trial testing End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility in Septic Shock in 60 participants. Status unknown.

Timeline

20 September 2022

Primary endpoint
27 February 2023

30 March 2023

Quick facts

Lead sponsor	Bozyaka Training and Research Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	60
Start date	20 September 2022
Primary completion	27 February 2023
Estimated completion	30 March 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility

Conditions studied

Septic Shock — all drugs for Septic Shock →
Hypovolemia — all drugs for Hypovolemia →
Sepsis — all drugs for Sepsis →

Sponsor

Bozyaka Training and Research Hospital

Who can join

18 and older, any sex, with Septic Shock or Hypovolemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Fluid therapy is important in patients with sepsis and septic shock. There are many invasive and non-invasive methods to assess fluid responsiveness in patients. The specificities and sensitivities of these methods are highly variable. The reason for our study was to determine end-tidal co2 and fluid responsiveness in septic shock patients. The aim of the study was to evaluate the fluid response using the End-tidal CO2 difference in septic shock patients receiving intubated mechanical ventilation support.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Easy method to determine fluid responsiveness in septic shock patients: end-tidal CO2 - a prospective observational study.
Özkarakaş H, Uçar O, Tekgül ZT, Ozmuk Ö, et al · · 2024 · PMID 38305657 · DOI 10.14744/tjtes.2024.37309

Verify or expand the search:

Other recruiting trials for Septic Shock

Currently open trials in the same condition.

NCT07179276 — Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock · NA · recruiting
NCT07383103 — Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock · Phase 4 · recruiting
NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
NCT07264543 — Early Methylene Blue in the Microhemodynamics of Septic Patients · Phase 2, PHASE3 · recruiting
NCT04855786 — External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients · NA · recruiting

Other Bozyaka Training and Research Hospital trials

Trials by the same sponsor.

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NCT06984653 — Effect of Scalp Block on Bispectral Index Values During Skull Pinning · completed
NCT06759506 — Can Perfusion Index and Cerebral Oxygen Saturation Trends Predict Low Cardiac Output in Pediatric Cardiovascular Surgeri · not yet recruiting
NCT06430918 — Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis · enrolling by invitation
NCT06029413 — Myo vs. Myofascial Injection for Myofascial Trigger Points · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05557461 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bozyaka Training and Research Hospital
Last refreshed: 25 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05557461.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing