Last reviewed · How we verify
NCT05555511
Perioperative Use of NAC to Prevent AKI in Patients With Pre-existing Moderate Renal Insufficiency Following Cardiac Surgery
NA trial testing Control Group in Kidney Injury, Acute in 46 participants. Status unknown.
26 January 2023
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 46 |
| Start date | 26 August 2022 |
| Primary completion | 26 January 2023 |
| Estimated completion | 26 February 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Control Group — full drug profile →
Conditions studied
- Kidney Injury, Acute — all drugs for Kidney Injury, Acute →
Sponsor
Ain Shams University
Who can join
18 and older, any sex, with Kidney Injury, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Acute kidney injury (AKI) or renal impairment is an established complication of cardiac surgery occurring with an incidence up to 30%, To date, no agent has conferred renal protection. Considerable interest has developed in the potential for Nacetylcysteine (NAC) to exert a renoprotective effect in patients undergoing cardiac surgery. Due to the beneficial effect of NAC on contrast nephropathy and its reported anti-inflammatory effects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05555511
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Control Group
Trials testing the same drug.
- NCT07498556 — Immediate Restoration of a New Implant With High Primary Stability · NA · not yet recruiting
- NCT07439289 — Turtle-Assisted Animal Interaction on Dental Anxiety and Physiological Parameters in Children · NA · not yet recruiting
- NCT07445711 — Effect of Guided Imagery and AI-Assisted Video on Pain During Uterine Involution Assessment in Postpartum Women: A Rando · NA · not yet recruiting
- NCT07418021 — Effects of Cold Spray and Buzzy Device an Pain and Fear During Penicillin Injection · NA · not yet recruiting
- NCT07500077 — Strength and Balance Integration in Maintenance Cardiac Rehabilitation for Older Adults · NA · recruiting
Other recruiting trials for Kidney Injury, Acute
Currently open trials in the same condition.
- NCT07030166 — A Machine Learning Prediction Model for Postoperative Acute Kidney Injury in Non-Cardiac Surgery Patients · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05555511 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 28 December 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05555511.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing