Who is sponsoring NCT05555069?

NCT05555069 is sponsored by Nikki Nollen, PhD, MA.

What drugs are being tested in NCT05555069?

Interventions in NCT05555069: Menthol-flavored electronic cigarette, Tobacco-flavored electronic cigarette.

What condition does NCT05555069 study?

NCT05555069 studies Smoking Reduction.

Is NCT05555069 still recruiting?

NCT05555069 is currently recruiting now. Last updated 23 January 2026.

Last reviewed 2026-01-23 · How we verify

NCT05555069

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

Recruiting now NA Last updated 23 January 2026

What this trial tests

NA trial testing Menthol-flavored electronic cigarette in Smoking Reduction in 800 participants. Currently enrolling.

Timeline

8 November 2022

Primary endpoint
31 December 2026

31 March 2027

Quick facts

Lead sponsor	Nikki Nollen, PhD, MA
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	800
Start date	8 November 2022
Primary completion	31 December 2026
Estimated completion	31 March 2027
Sites	1 location across United States

Drugs / interventions tested

Menthol-flavored electronic cigarette
Tobacco-flavored electronic cigarette

Conditions studied

Smoking Reduction — all drugs for Smoking Reduction →

Sponsor

Nikki Nollen, PhD, MA

Who can join

21 and older, any sex, with Smoking Reduction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will compare the efficacy of menthol-flavored versus tobacco-flavored 4th generation nicotine salt-based pod-system e-cigarettes in facilitating a switch from combustible cigarettes to e-cigarettes in adult menthol smokers.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Electronic cigarettes for smoking cessation.
Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2024 · cited 94× · PMID 38189560 · DOI 10.1002/14651858.cd010216.pub8
Electronic cigarettes for smoking cessation.
Lindson N, Butler AR, McRobbie H, Bullen C, et al · · 2025 · cited 32× · PMID 39878158 · DOI 10.1002/14651858.cd010216.pub9

Verify or expand the search:

Other recruiting trials for Smoking Reduction

Currently open trials in the same condition.

NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting
NCT06693700 — A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home · NA · recruiting
NCT06675526 — Detour: a Smartphone Game to Help Youth Quit Smoking · NA · recruiting
NCT06458205 — Impact of Multi-Component Interventions on High-Risk COPD Smokers · NA · active not recruiting
NCT06311162 — Early Life Intervention in Pediatrics Supported by E-health - SMOKE · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05555069 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nikki Nollen, PhD, MA
Last refreshed: 23 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05555069.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing